Evidence map›Paper›PMID 35718332›Full record

ArticleSLAS technology2022

Buildout and integration of an automated high-throughput CLIA laboratory for SARS-CoV-2 testing on a large urban campus.

Lena Landaverde, David McIntyre, James Robson, Dany Fu, Luis Ortiz, Rita Chen, Samuel M D Oliveira, Andy Fan, Amy Barrett, Stephen P Burgay and 27 more

Abstract read
In one paragraph

Article in SLAS technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Lena LandaverdePrecision Diagnostics Center, Boston University, Boston, MA; Biomedical Engineering, College of Engineering, Boston University, Boston, MA; Boston University Clinical Testing Laboratory, Boston University, Boston, MA.
David McIntyreBiomedical Engineering, College of Engineering, Boston University, Boston, MA; Design, Automation, Manufacturing, and Prototyping Laboratory, Boston University, Boston, MA; Biological Design Center, Boston University, Boston, MA.
James RobsonBiomedical Engineering, College of Engineering, Boston University, Boston, MA.
Dany FuDesign, Automation, Manufacturing, and Prototyping Laboratory, Boston University, Boston, MA; Software & Application Innovation Lab, Hariri Institute for Computing, Boston University, Boston, MA; Department of Biology, Boston University, Boston, MA.
Luis OrtizBiomedical Engineering, College of Engineering, Boston University, Boston, MA; Design, Automation, Manufacturing, and Prototyping Laboratory, Boston University, Boston, MA; Biological Design Center, Boston University, Boston, MA.
Rita ChenDesign, Automation, Manufacturing, and Prototyping Laboratory, Boston University, Boston, MA; Electrical and Computer Engineering, Boston University, Boston, MA.
Samuel M D OliveiraDesign, Automation, Manufacturing, and Prototyping Laboratory, Boston University, Boston, MA; Electrical and Computer Engineering, Boston University, Boston, MA.
Andy FanBiomedical Engineering, College of Engineering, Boston University, Boston, MA.
Amy BarrettOffice of the Provost, Boston University, Boston, MA.
Stephen P BurgayOffice of External Affairs, Boston University, Boston, MA.
Stephen ChoateInformation Services & Technology, Boston University, Boston, MA.
David CorbettHealth Information Privacy Resources, Boston University, Boston, MA.
Lynn Doucette-StammBoston University Clinical Testing Laboratory, Boston University, Boston, MA.
Kevin GonzalesBU Healthway, Boston University, Boston, MA; Office of Research, Boston University, Boston, MA.
Davidson H HamerPrecision Diagnostics Center, Boston University, Boston, MA; Department of Global Health, Boston University School of Public Health, Boston University, Boston, MA; Section of Infectious Disease, Department of Medicine, Boston University School of Medicine, Boston, MA; National Emerging Infectious Disease Laboratory, Boston, MA.
Lilly HuangOffice of General Counsel, Boston University, Boston, MA.
Shari HuvalInformation Services & Technology, Boston University, Boston, MA.
Christopher KnightInformation Services & Technology, Boston University, Boston, MA.
Carrie LandaStudent Health Services, Healthway, Boston University School of Public Health, Boston, MA.
Diane LindquistHealth Privacy and Compliance, Boston University, Boston, MA.
Kelly LockardContinuous Improvement & Data Analytics, Boston University, Boston, MA.
Trevor L MacdowellInformation Services & Technology, Boston University, Boston, MA.
Elizabeth MauroInformation Services & Technology, Boston University, Boston, MA.
Colleen McGintyOperations, Boston University, Boston, MA.
Candice MillerBoston University Clinical Testing Laboratory, Boston University, Boston, MA.
Maura MonahanInformation Services & Technology, Boston University, Boston, MA.
Randall MooreSourcing and Procurement, Boston University, Boston, MA.
Judy PlattStudent Health Services, Healthway, Boston University School of Public Health, Boston, MA.
Lloyd RollesStudent Health Services, Healthway, Boston University School of Public Health, Boston, MA.
Jeffrey RoySourcing and Procurement, Boston University, Boston, MA.
Tracey SchroederInformation Services & Technology, Boston University, Boston, MA.
Dean R TolanBoston University Clinical Testing Laboratory, Boston University, Boston, MA; HFI Laboratory, Boston University, Boston, MA.
Ann ZaiaOccupational Health Center, Boston University, Boston, MA.
Robert A BrownCollege of Engineering, Boston University, Boston, MA; Office of the President, Boston University, Boston, MA.
Gloria WatersOffice of Research, Boston University, Boston, MA; College of Health and Rehabilitation Services, Sargent College, Boston University, Boston, MA.
Douglas DensmoreDesign, Automation, Manufacturing, and Prototyping Laboratory, Boston University, Boston, MA; Biological Design Center, Boston University, Boston, MA; Electrical and Computer Engineering, Boston University, Boston, MA.
Catherine M KlapperichPrecision Diagnostics Center, Boston University, Boston, MA; Biomedical Engineering, College of Engineering, Boston University, Boston, MA; Boston University Clinical Testing Laboratory, Boston University, Boston, MA. Electronic address: catherin@bu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2019, the first cases of SARS-CoV-2 were detected in Wuhan, China, and by early 2020 the first cases were identified in the United States. SARS-CoV-2 infections increased in the US causing many states to implement stay-at-home orders and additional safety precautions to mitigate potential outbreaks. As policies changed throughout the pandemic and restrictions lifted, there was an increase in demand for COVID-19 testing which was costly, difficult to obtain, or had long turn-around times. Some academic institutions, including Boston University (BU), created an on-campus COVID-19 screening protocol as part of a plan for the safe return of students, faculty, and staff to campus with the option for in-person classes. At BU, we put together an automated high-throughput clinical testing laboratory with the capacity to run 45,000 individual tests weekly by Fall of 2020, with a purpose-built clinical testing laboratory, a multiplexed reverse transcription PCR (RT-qPCR) test, robotic instrumentation, and trained staff. There were many challenges including supply chain issues for personal protective equipment and testing materials in addition to equipment that were in high demand. The BU Clinical Testing Laboratory (CTL) was operational at the start of Fall 2020 and performed over 1 million SARS-CoV-2 PCR tests during the 2020-2021 academic year.

Indexed as

COVID-19SARS-CoV-2COVID-19 TestingHumansPandemicsReal-Time Polymerase Chain ReactionUnited States

Identifiers

PMID35718332
PMCPMC9212990

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.