Evidence map›Paper›PMID 35718306›Full record

ArticleJournal of cardiac failure2022

Vaccines, Antibodies and Donors: Varying Attitudes and Policies Surrounding COVID-19 and Heart Transplantation.

Ersilia M Defilippis, Larry A Allen, Ankeet S Bhatt, Susan Joseph, Michelle Kittleson, Orly Vardeny, Mark H Drazner, Anuradha Lala

Open access · greenAbstract read
In one paragraph

Article in Journal of cardiac failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Utilization of COVID-19 positive donors for Heart transplantation and associated short-term outcomes.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 1 country.

Ersilia M DefilippisDivision of Cardiology, Columbia University Irving Medical Center, New York, New York.
Larry A AllenDivision of Cardiology, University of Colorado School of Medicine, Aurora, Colorado.
Ankeet S BhattDivision of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Susan JosephDepartment of Cardiology, University of Maryland Medical Center, Baltimore, Maryland.
Michelle KittlesonDepartment of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California.
Orly VardenyCenter for Care Delivery and Outcomes Research, Minneapolis VA Health Care System, and University of Minnesota, Minneapolis, Minnesota.
Mark H DraznerDivision of Cardiology, University of Texas Southwestern Medical Center, Dallas, Texas.
Anuradha LalaZena and Michael A. Wiener Cardiovascular Institute & Department of Population Health Science, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: anu.lala@mountsinai.org.
Brigham and Women's Hospital · USCedars-Sinai Medical Center · USColumbia University Irving Medical Center · USMinneapolis VA Health Care System · USMount Sinai Hospital · USThe University of Texas Southwestern Medical Center · USUniversity of Colorado Denver · USUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere are varied opinions in the United States regarding many aspects of care related to COVID-19. The purpose of this study was to examine the opinions of health care personnel and the policies of heart transplant centers concerning practices for the prevention and treatment of COVID-19 in donors and recipients of heart transplants.

methodsTwo anonymous, electronic web-based surveys were developed: 1 was administered to health care personnel through a mailing list maintained by the Heart Failure Society of America (HFSA); another was administered to U.S. medical adult and pediatric heart transplant (HT) program directors. Individual and group e-mails were sent with an embedded link to the respective surveys in February 2022.

resultsA total of 176 individuals (8.6%) responded to the survey administered through the HFSA. Of medical directors of transplant programs, 78 (54% response rate) completed a separate survey on their centers' policies. Although 95% (n = 167) of individuals indicated vaccination against COVID-19 should be required prior to HT, only 67% (n = 52) of centers mandated that practice. Similarly, 61% of individuals thought vaccination should be required prior to HT for caregivers, but only 13% of transplant centers mandated caregiver vaccination. Of the centers, 63% reported considering donors despite histories of recent COVID-19 infection (within 3 months), and 47% considered donors with current positive polymerase chain reaction tests. Regarding post-transplant care, only 22% of programs routinely measured antibodies to COVID-19, and 71% used tixagevimab/cilgavimab (Evusheld) for pre-exposure prophylaxis.

conclusionsThere were significant differences between individual preferences and centers' practices with respect to COVID-19 management of candidates for and recipients of HT. Additionally, there was wide variation in policies among centers, reflecting the need for further study to inform consistent guidance and recommendations across centers to optimize equitable care for this high-risk patient population.

Indexed as

COVID-19Heart FailureHeart TransplantationVaccinesAttitudeChildHumansPolicyUnited StatesVaccinesCOVID-19donorheart transplantationvaccination

Identifiers

PMID35718306
PMCPMC9212876
OpenAlexW4283017206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.