Evidence map›Paper›PMID 35717676›Full record

ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2022

Relationship between anal functional lumen imaging probe (EndoFLIP®) results and the clinical presentation of faecal incontinence.

Charlotte Desprez, Guillaume Gourcerol, Céline Savoye-Collet, Valérie Bridoux, Thomas Duflot, Anne-Marie Leroi

Open access · hybridAbstract read
In one paragraph

Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Observational
  2. Review
  3. Relationship between anal functional lumen imaging probe (EndoFLIP®) results and the clinical presentation of faecal incontinence.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Charlotte DesprezDepartment of Digestive Physiology, Rouen University Hospital, Rouen, France.
Guillaume GourcerolDepartment of Digestive Physiology, CIC-CRB 1404, Inserm U1073, CHU Rouen, 'Normandie Université, UNIROUEN, Rouen, France.
Céline Savoye-ColletDepartment of Radiology, 'Normandie Université, UNIROUEN, CHU Rouen, Rouen, France.
Valérie BridouxDepartment of Digestive Surgery, Inserm U1073, 'Normandie Université, UNIROUEN, CHU Rouen, Rouen, France.
Thomas DuflotDepartment of Pharmacology, 'Normandie Université, UNIROUEN, Inserm U1096, CHU Rouen, Rouen, France.ORCID 0000-0002-8730-284X
Anne-Marie LeroiDepartment of Digestive Physiology, CIC-CRB 1404, Inserm U1073, CHU Rouen, 'Normandie Université, UNIROUEN, Rouen, France.
Inserm · FRInstitute for Biomedicine · ITNormandie Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimFaecal incontinence (FI) subtypes (urge, passive, mixed) are linked to the physiopathological mechanism of FI. Previous studies have failed to demonstrate a consistent relationship between FI subtype and anal sphincter dysfunction. Our aim was to evaluate the relationship between anal sphincter function, assessed using the new EndoFLIP® technology, and FI subtype.

methodPatients referred for FI were prospectively enrolled between October 2015 and May 2021 in a registry, and data were retrospectively examined. Each patient underwent a clinical assessment as well as three-dimensional high-resolution or water-perfused anorectal manometry, anal EndoFLIP®, and anorectal electrophysiological and endoanal ultrasound tests. The results of the investigations were compared across FI subtypes.

resultsThe cohort included 133 patients, 54 (41%) of whom met the criteria for urge FI, 40 (30%) for passive FI and 39 (29%) for mixed FI. The resting anal distensibility index (DI) at 50 ml of distension was significantly lower in patients with urge FI than in patients with passive FI (p = 0.04). At rest, a DI at 50 ml of distension ≥7.3 mm

conclusionThe anal sphincter DI using the EndoFLIP® system displayed poor predictive performance in distinguishing among FI subtypes.

Indexed as

Fecal IncontinenceAnal CanalHumansManometryRetrospective StudiesUltrasonography

Identifiers

PMID35717676
PMCPMC9795963
OpenAlexW4283123255

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.