Evidence map›Paper›PMID 35717469›Full record

ArticleInternational urogynecology journal2023

The effect of preoperative scopolamine patch use on postoperative urinary retention in urogynecologic surgeries.

Alexa Courtepatte, Maura Kelly, Vatche A Minassian

Open access · greenAbstract readComparative Study
In one paragraph

Article in International urogynecology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Preoperative Analgesia in Midurethral Sling: A Cohort Study.International urogynecology journal · 2025
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Alexa CourtepatteDivision of Urogynecology, Department of OB/GYN, Mass General Brigham, 500 Brookline Ave, Suite E, Boston, MA, 02215, USA. acourtepatte@bwh.harvard.edu.ORCID 0000-0003-2402-240X
Maura KellyDivision of Urogynecology, Department of OB/GYN, Mass General Brigham, 500 Brookline Ave, Suite E, Boston, MA, 02215, USA.
Vatche A MinassianDivision of Urogynecology, Department of OB/GYN, Mass General Brigham, 500 Brookline Ave, Suite E, Boston, MA, 02215, USA.
Mass General Brigham · USCenter for Systems Biology · US

Funding

The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0M
NCATS NIH HHS UL1 TR002541
6 · The paper itself

Abstract

introduction and hypothesisThis study aims to determine whether the use of preoperative transdermal scopolamine is associated with an increased risk of postoperative urinary retention in urogynecologic surgeries.

methodsThis is a retrospective chart review study of women who underwent surgery between January 1, 2018, and December 31, 2020. Patients who received a scopolamine patch versus those who did not were compared using demographic and perioperative variables utilizing Pearson's chi-squared test and t-test of Wilcoxon rank-sum. A logistic regression was performed to evaluate the effect of scopolamine on the patients' postoperative voiding trial results, controlling for confounders. P-value < 0.05 was considered statistically significant.

resultsA total of 449 women underwent a vaginal or laparoscopic hysterectomy, midurethral sling placement, uterosacral or sacrospinous ligament suspension, sacrocolpopexy, anterior/posterior colporrhaphy, or other urogynecologic surgeries with 109 (24.2%) having received transdermal scopolamine. A significantly higher number of women with preoperative scopolamine [n = 50 (45.9%)] failed their voiding trial compared to those without scopolamine [n = 100 (29.4%), p = 0.0016]. The adjusted model yielded an odds ratio of 1.75 (95% CI: 1.08-2.85) of a failed voiding trial in the scopolamine group. When comparing the odds of failing voiding trial by surgery type, those with a midurethral sling placed during surgery had an adjusted odds ratio of 3.12 (95% CI: 2.01-4.87), as compared to those without a midurethral sling.

conclusionsUse of a transdermal scopolamine patch for nausea and vomiting prophylaxis is associated with increased risk of postoperative urinary retention across all urogynecologic surgeries.

Indexed as

Suburethral SlingsUrinary Incontinence, StressUrinary RetentionFemaleHumansPostoperative ComplicationsRetrospective StudiesScopolamineScopolaminePelvic organ prolapsePostoperative nausea and vomitingScopolamineUrinary incontinenceUrinary retentionUrogenital surgery procedures

Identifiers

PMID35717469
PMCPMC10103139
OpenAlexW4283121930

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.