ArticleDevelopmental cognitive neuroscience2022
Does pubertal stage mediate the association between family environment and structure and function of the amygdala-mPFC circuit? A replication study of the longitudinal ABCD cohort.
Article in Developmental cognitive neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 21 citations in OpenAlex.
- Childhood adversity and psychotic-like experiences in adolescence: Investigating a pathway via disrupted pubertal and grey matter development.JCPP advances · 2026Article
- In relation to anxiety severity, puberty moderates functional connectivity between the amygdala and anterior cingulate cortex for negative relative to neutral stimuli during an emotional categorization task.Developmental cognitive neuroscience · 2026Article
- Perceived Racism, Brain Development, and Internalizing and Externalizing Symptoms: Findings From the ABCD Study.Journal of the American Academy of Child and Adolescent Psychiatry · 2026Article
- Prenatal Cannabis Exposure Shaping Altered Brain Connectivity: Neural Correlates of Cognitive and Mental Health Variability in Offspring.Research square · 2026Article
- Potential predictors of future suicide attempts in adolescents assigned female at birth.Journal of affective disorders · 2026Article
- Associations between socioeconomic status and mental health trajectories during early adolescence: Findings from the Adolescent Brain Cognitive Development study.JCPP advances · 2025Article
- The role of pubertal development in the association between trauma and internalising symptoms in female youth.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- The effects of adverse life events on brain development in the ABCD study®: a propensity-weighted analysis.Molecular psychiatry · 2025Article
- Sexual Minority Stress: Preliminary Evidence of Accelerated Pubertal Development in Early Adolescence.Journal of adolescence · 2025Article
- Associations of interpersonal and socioeconomic early life adversity dimensions with adolescents' corticolimbic circuits, cognition, and mental health.Translational psychiatry · 2025Article
- Cognitive and psychiatric relevance of dynamic functional connectivity states in a large (N > 10,000) children population.Molecular psychiatry · 2025Article
- Mean Diffusivity of the Left Caudal Anterior Cingulate Cortex and Past Major Depressive Disorder in Adolescents: Evidence from the ABCD Study.Journal of cellular neuroscience · 2025Article
- Adolescent brain cognitive development study: Longitudinal methods, developmental findings, and associations with environmental risk factors.Developmental cognitive neuroscience · 2023Article
- Childhood trauma, earlier pubertal timing, and psychopathology in adolescence: The role of corticolimbic development.Developmental cognitive neuroscience · 2023Article
- Mediating effect of pubertal stages on the family environment and neurodevelopment: An open-data replication and multiverse analysis of an ABCD StudyNeuroimage. Reports · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
Abstract
Psychosocial acceleration theory suggests that early stress accelerates pubertal development. Using half of the baseline Adolescent Brain and Cognitive Development (ABCD) cohort, Thijssen et al. (2020) provide support that accelerated puberty following stressful family environments may promote neurodevelopment. Here, we replicate and extend those analyses using 1) data from the second half of the ABCD sample (n = 3300 +, ages 9-10), and 2) longitudinal imaging data from the original sample (n = 1800 +, ages 11-12). A family environment latent variable was created and related to anterior cingulate cortex (ACC) thickness, area, white matter fractional anisotropy, amygdala volume, and cingulo-opercular network (CON)-amygdala resting-state functional connectivity. Results from the independent sample replicate the mediating effects of family environment through pubertal stage on amygdala-CON functional connectivity. Sex-stratified analyses show indirect effects via pubertal stage in girls; boys show evidence for direct associations. Analyses using wave 2 imaging data or wave 2-wave 1 difference scores from the originally-analyzed sample replicate the resting-state indirect effects. The current paper replicates the mediating role for puberty in the association between family environment and neurodevelopment. As both direct and indirect associations were found, puberty may be one of multiple mechanisms driving accelerated neurodevelopment following environmental stress.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.