SynthesisPsychiatry research2022
COVID-19 and first manic episodes: a systematic review.
Synthesis in Psychiatry research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Psychobiotic Effects of Postbiotics in Depression, Psychosis and Mania.Health promotion perspectives · 2026Review
- COVID-19 and Mania: A Case with a One-year Follow UP.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2025Article
- The transdiagnostic role of event-related rumination on internalizing and externalizing symptoms during the pandemic: a two-wave longitudinal study.Frontiers in psychology · 2025Article
- Association Between COVID-19 and Neurological Diseases: Evidence from Large-Scale Mendelian Randomization Analysis and Single-Cell RNA Sequencing Analysis.Molecular neurobiology · 2024Article
- Steroid-induced mania in a patient with previously well-controlled organic bipolar 1-like affective disorder secondary to acquired brain injury: case report and literature review.Discover mental health · 2024Article
- The impact of the COVID-19 pandemic on rates of adolescents receiving psychopharmacological medication in Austria.Child and adolescent psychiatry and mental health · 2024Article
- Examining the Relationships between the Incidence of Infectious Diseases and Mood Disorders: An Analysis of Data from the Global Burden of Disease Studies, 1990-2019.Diseases (Basel, Switzerland) · 2023Article
- Facing the Shadow Pandemic: Correlation and Trend Analyses of Violence Reports from Women to the Italian National Anti-Violence Number during 2021.Healthcare (Basel, Switzerland) · 2023Article
- A rare clinical presentation after COVID-19: Manic episode with psychotic features.Psychiatry research case reports · 2023Article
- The Korean Version of Pandemic Stress Questionnaire: Validation in Korean Population.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2023Article
- Psychiatric consequences and issues of long COVID on patients with prior psychiatric comorbidities: a scoping review.Frontiers in psychiatry · 2023Article
- First Manic Episode Following SARS-CoV-2 Infection.Cureus · 2023Article
- Bipolar spectrum disorders in neurologic disorders.Frontiers in psychiatry · 2022Review
Corrections and comments
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sars-CoV-2 is a respiratory virus that can access the central nervous system, as indicated by the presence of the virus in patients' cerebrospinal fluid and the occurrence of several neurological syndromes during and after COVID-19. Growing evidence indicates that Sars-CoV-2 can also trigger the acute onset of mood disorders or psychotic symptoms. COVID-19-related first episodes of mania, in subjects with no known history of bipolar disorder, have never been systematically analyzed. Thus, the present study assesses a potential link between the two conditions. This systematic review analyzes cases of first appearance of manic episodes associated with COVID-19. Clinical features, pharmacological therapies, and relationships with pre-existing medical conditions are also appraised. Medical records of twenty-three patients fulfilling the current DSM-5 criteria for manic episode were included. Manic episodes started, on average, after 12.71±6.65 days from the infection onset. Psychotic symptoms were frequently reported. 82.61% of patients exhibited delusions, whereas 39.13% of patients presented hallucinations. A large discrepancy in the diagnostic workups was observed. Mania represents an underestimated clinical presentation of COVID-19. Further studies should focus on the pathophysiological substrates of COVID-19-related mania and pursue appropriate and specific diagnostic and therapeutic workups.
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