Evidence map›Paper›PMID 35716467›Full record

ArticleUltrasonics sonochemistry2022

Enhancement of ultrasound-assisted extraction of sulforaphane from broccoli seeds via the application of microwave pretreatment.

Yanbing Liu, Di Zhang, Xiaodan Li, Junxia Xiao, Liping Guo

Abstract read
In one paragraph

Article in Ultrasonics sonochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Extraction, purification and antioxidant activity of flavonoids fromFrontiers in bioengineering and biotechnology · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yanbing LiuCollege of Food Science and Engineering, Qingdao Agricultural University, Qingdao, Shandong 266109, China.
Di ZhangCollege of Food Science and Engineering, Qingdao Agricultural University, Qingdao, Shandong 266109, China.
Xiaodan LiCollege of Food Science and Engineering, Qingdao Agricultural University, Qingdao, Shandong 266109, China; Qingdao Special Food Research Institute, Qingdao, Shandong 266109, China.
Junxia XiaoCollege of Food Science and Engineering, Qingdao Agricultural University, Qingdao, Shandong 266109, China; Qingdao Special Food Research Institute, Qingdao, Shandong 266109, China.
Liping GuoCollege of Food Science and Engineering, Qingdao Agricultural University, Qingdao, Shandong 266109, China; Qingdao Special Food Research Institute, Qingdao, Shandong 266109, China. Electronic address: happyglp@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, microwave pretreatment and grinding treatment were used to enhance sulforaphane formation, then ultrasonic-assisted extraction (UAE) was applied to extract sulforaphane using simultaneous hydrolysis and extraction method. The effects of various parameters, which were ultrasonic time,ultrasonic power, solid-water ratio and solid-ethyl acetate ratio on the extraction rate of sulforaphane were investigated. The results showed that microwave pretreatment enhanced sulforaphane formation. Excessive size reduction did not increase or even reduced extraction rate of sulforaphane. Simultaneous hydrolysis and extraction significantly increased extraction rate of sulforaphane compared to hydrolysis followed by extraction. UAE accelerated mass transfer and the solubilization of the targeted compounds due to the acoustic cavitation effect, thus enhanced enzymatic hydrolysis of glucoraphanin and the extraction rate of sulforaphane. The extraction rate of sulforaphane using UAE with simultaneous hydrolysis and extraction was 4.07-fold of the conventional extraction method. UAE was an effective method to extract sulforaphane from broccoli seeds since it led to higher yield of sulforaphane in a much shorter extraction time.

Indexed as

BrassicaIsothiocyanatesMicrowavesSeedsSulfoxidesIsothiocyanatessulforaphaneSulfoxidesBroccoli seedsMicrowave pretreatmentSimultaneous hydrolysis and extractionSulforaphaneUltrasonic-assisted extraction

Identifiers

PMID35716467
PMCPMC9213254

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.