Evidence map›Paper›PMID 35716267›Full record

ArticleArchives of virology2022

Predominance and first complete genomic characterization of canine parvovirus 2b in Turkey.

Hasan Abayli, Oznur Aslan, Kenan Cağrı Tumer, Kezban Can-Sahna, Sukru Tonbak

Open access · bronzeAbstract read
In one paragraph

Article in Archives of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hasan AbayliDepartment of Virology, Faculty of Veterinary Medicine, Firat University, 23110, Elazig, Turkey. habayli@firat.edu.tr.ORCID http://orcid.org/0000-0003-2116-105X
Oznur AslanDepartment of Internal Medicine, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkey.
Kenan Cağrı TumerDepartment of Internal Medicine, Faculty of Veterinary Medicine, Firat University, Elazig, Turkey.
Kezban Can-SahnaDepartment of Virology, Faculty of Veterinary Medicine, Firat University, 23110, Elazig, Turkey.
Sukru TonbakDepartment of Virology, Faculty of Veterinary Medicine, Firat University, 23110, Elazig, Turkey.
Fırat University · TRErciyes University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral enteritis is a significant threat to domestic dogs. The two primary pathogens that cause viral enteritis in dogs are canine coronavirus (CCoV) and canine parvovirus (CPV). In this study, we investigated the occurrence of CPV-2, CCoV, and canine circovirus coinfection by characterizing circulating subtypes of CPV-2 in faecal samples from symptomatic dogs admitted to veterinary clinics located in Ankara, Elazığ, Kayseri, and Kocaeli provinces of Turkey, between 2019 and 2022. Virus detection by PCR and RT-PCR revealed that CPV-2 was present in 48 (77.4%) samples, and no other agents were detected. Based on the occurrence of the codon GAT at positions 1276 to 1278 (coding for aspartate at residue 426) of VP2, all CPV-2 isolates were confirmed to be of the CPV-2b subtype. The complete genome sequences of two CPV-2b isolates showed a high degree of similarity to and phylogenetic clustering with Australian and East Asian strains/isolates. The predominant CPV strain circulating in the three different regions of Turkey was found to be a CPV-2b strain containing the amino acid substitutions at Y324I and T440A, which commonly contribute to immune escape. This is the first report of complete genomic analysis of CPV-2 isolates circulating in symptomatic domestic dogs in Turkey. The evolution of CPV-2 has raised questions about the efficacy of current vaccination regimes and highlights the importance of monitoring the emergence and spread of new CPV-2 variants.

Indexed as

Coronavirus, CanineDog DiseasesEnteritisParvoviridae InfectionsParvovirus, CanineAnimalsAustraliaDogsGenomicsPhylogenyTurkey

Identifiers

PMID35716267
PMCPMC9206223
OpenAlexW4283068286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.