Evidence map›Paper›PMID 35716231›Full record

ReviewDiscover oncology2022

Glioma extracellular vesicles for precision medicine: prognostic and theragnostic application.

Hany E Marei, Asmaa Althani, Nahla Afifi, Anwarul Hasan, Thomas Caceci, Ingrid Cifola, Sara Caratelli, Giuseppe Sconocchia, Igea D'Agnano, Carlo Cenciarelli

Open access · goldAbstract readReview
In one paragraph

Review in Discover oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  3. Article
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  7. Nuclear Medicine and Cancer Theragnostics: Basic Concepts.Diagnostics (Basel, Switzerland) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 4 countries.

Hany E MareiDepartment of Cytology and Histology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, 35116, Egypt. hanymarei@mans.edu.eg.
Asmaa AlthaniBiomedical Research Center, Qatar University, Doha, Qatar.
Nahla AfifiQatar Biobank, Doha, Qatar.
Anwarul HasanDepartment of Mechanical and Industrial Engineering, College of Engineering, Qatar University, Doha, Qatar.
Thomas CaceciBiomedical Sciences, Virginia Maryland College of Veterinary Medicine, Blacksburg, VA, USA.
Ingrid CifolaInstitute for Biomedical Technologies (ITB)-CNR, Segrate, Italy.
Sara CaratelliInstitute of Translational Pharmacology (IFT)-CNR, Rome, Italy.
Giuseppe SconocchiaInstitute of Translational Pharmacology (IFT)-CNR, Rome, Italy.
Igea D'Agnano *Institute for Biomedical Technologies (ITB)-CNR, Segrate, Italy.
Carlo Cenciarelli *Institute of Translational Pharmacology (IFT)-CNR, Rome, Italy.
Istituto di Farmacologia Traslazionale · ITInstitute of Biomedical Technologies · ITQatar University · QAMansoura University · EGQatar Central Bank · QAVirginia–Maryland College of Veterinary Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

EV produced by tumour cells carry a diverse population of proteins, lipids, DNA, and RNA molecules throughout the body and appear to play an important role in the overall development of the disease state, according to growing data. Gliomas account for a sizable fraction of all primary brain tumours and the vast majority of brain malignancies. Glioblastoma multiforme (GBM) is a kind of grade IV glioma that has a very dismal prognosis despite advancements in diagnostic methods and therapeutic options. The authors discuss advances in understanding the function of extracellular vesicles (EVs), in overall glioma growth, as well as how recent research is uncovering the utility of EVs in glioma diagnostics, prognostic and therapeutics approaches.

Indexed as

DiagnosisExtracellular vesiclesGBMGSCsPrognosisTherapy

Identifiers

PMID35716231
PMCPMC9206693
OpenAlexW4283070678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.