Evidence map›Paper›PMID 35715717›Full record

ArticleBiological trace element research2023

Iron Supplementation and Exercise During Pregnancy: Effects on Behavior and the Dopaminergic System.

Daubian-Nosé P, Franco B, De Fante T, Forte Ldm, Manchado-Gobatto F B, Bezerra R M, Manconi M, Torsoni A S, Esteves A M

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daubian-Nosé P *Faculdade de Ciências Aplicadas, Universidade Estadual de Campinas, Jardim Santa Luiza, Rua Pedro Zaccaria, Limeira, São Paulo, 1300CEP 13484350, Brazil.
Franco B *Faculdade de Educação Física, Universidade Estadual de Campinas, Limeira, Brazil.
De Fante TFaculdade de Ciências Aplicadas, Universidade Estadual de Campinas, Jardim Santa Luiza, Rua Pedro Zaccaria, Limeira, São Paulo, 1300CEP 13484350, Brazil.
Forte LdmFaculdade de Ciências Aplicadas, Universidade Estadual de Campinas, Jardim Santa Luiza, Rua Pedro Zaccaria, Limeira, São Paulo, 1300CEP 13484350, Brazil.
Manchado-Gobatto F BFaculdade de Ciências Aplicadas, Universidade Estadual de Campinas, Jardim Santa Luiza, Rua Pedro Zaccaria, Limeira, São Paulo, 1300CEP 13484350, Brazil.
Bezerra R MFaculdade de Ciências Aplicadas, Universidade Estadual de Campinas, Jardim Santa Luiza, Rua Pedro Zaccaria, Limeira, São Paulo, 1300CEP 13484350, Brazil.
Manconi MSleep and Epilepsy Center, Neurocenter of Southern Switzerland, Civic Hospital of Lugano (EOC), Lugano, Switzerland.
Torsoni A SFaculdade de Ciências Aplicadas, Universidade Estadual de Campinas, Jardim Santa Luiza, Rua Pedro Zaccaria, Limeira, São Paulo, 1300CEP 13484350, Brazil.
Esteves A MFaculdade de Ciências Aplicadas, Universidade Estadual de Campinas, Jardim Santa Luiza, Rua Pedro Zaccaria, Limeira, São Paulo, 1300CEP 13484350, Brazil. andrea.esteves@fca.unicamp.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although it is known that regular physical activity is recommended as part of a healthy lifestyle, the number of data concerning efficacy of exercise and your relationship with a demand for iron during pregnancy is limited. The purpose of this study was to evaluate the relationship between iron supplementation and exercise during pregnancy on the behavior of rats. Molecular variables dopamine transporter (DAT) and dopamine receptor (D2) related to the locomotor behavior in response to the exercise and the iron supplemented diet were investigated. Sixty-day-old female Wistar rats were used. The pregnant rats were distributed into the following groups: standard diet (SD, n = 7), iron supplementation (IS, n = 9), exercise (EX, n = 10), and exercise + iron supplementation (EX + IS, n = 9). All rats in both the pregnant and non-pregnant groups were submitted to open-field tests. The iron supplementation diet was shown to reduce locomotor behaviors, with reduced central and peripheral ambulation, reduced rearing, and increased freezing. On the other hand, physical exercise caused an increase in central and peripheral ambulation, and in rearing. The expression of the D2 receptor protein and the dopamine transporter DAT did not show changes with the interventions over 21 days of pregnancy. In this context, the present study demonstrated that both iron supplementation and exercise exerted an influence during pregnancy on the behavior of rats, however, with different effects.

Indexed as

Dopamine Plasma Membrane Transport ProteinsIronAnimalsDietDietary SupplementsDopamineFemalePregnancyRatsRats, WistarDopamineDopamine Plasma Membrane Transport ProteinsIronAnimal modelBehaviorIron supplementationPhysical activityPregnancy

Identifiers

PMID35715717

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.