Evidence map›Paper›PMID 35715582›Full record

ArticleInsights into imaging2022

What MRI-based tumor size measurement is best for predicting long-term survival in uterine cervical cancer?

Njål Lura, Kari S Wagner-Larsen, David Forsse, Jone Trovik, Mari K Halle, Bjørn I Bertelsen, Øyvind Salvesen, Kathrine Woie, Camilla Krakstad, Ingfrid S Haldorsen

Open access · goldAbstract read
In one paragraph

Article in Insights into imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Prognostic significance of Standard Uptake Value (SUVAbdominal radiology (New York) · 2025
    Article
  5. Tumor ADC value predicts outcome and yields refined prognostication in uterine cervical cancer.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  6. Review
  7. Article
  8. Staging by imaging in gynecologic cancer and the role of ultrasound: an update of European joint consensus statements.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2024
    Review
  9. Review
  10. Article
  11. Nanoparticle-Based Techniques for Bladder Cancer Imaging: A Review.International journal of molecular sciences · 2023
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Njål LuraDepartment of Radiology, Mohn Medical Imaging and Visualization Centre, Haukeland University Hospital, Jonas Lies vei 65, 5021, Bergen, Norway. Njal.lura@uib.no.ORCID http://orcid.org/0000-0002-0508-6881
Kari S Wagner-LarsenDepartment of Radiology, Mohn Medical Imaging and Visualization Centre, Haukeland University Hospital, Jonas Lies vei 65, 5021, Bergen, Norway.
David ForsseDepartment of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.
Jone TrovikDepartment of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.
Mari K HalleDepartment of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.
Bjørn I BertelsenDepartment of Pathology, Haukeland University Hospital, Bergen, Norway.
Øyvind SalvesenClinical Research Unit, Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
Kathrine WoieDepartment of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.
Camilla KrakstadDepartment of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.
Ingfrid S HaldorsenDepartment of Radiology, Mohn Medical Imaging and Visualization Centre, Haukeland University Hospital, Jonas Lies vei 65, 5021, Bergen, Norway.
Haukeland University Hospital · NONorwegian University of Science and Technology · NO

Funding

Helse Vest F-12512Norwegian research council 311350Trond Mohn stiftelse BFS2018TMT06
6 · The paper itself

Abstract

backgroundTumor size assessment by MRI is central for staging uterine cervical cancer. However, the optimal role of MRI-derived tumor measurements for prognostication is still unclear. MATERIAL AND

methodsThis retrospective cohort study included 416 women (median age: 43 years) diagnosed with cervical cancer during 2002-2017 who underwent pretreatment pelvic MRI. The MRIs were independently read by three radiologists, measuring maximum tumor diameters in three orthogonal planes and maximum diameter irrespective of plane (MAX

resultsAll MRI tumor size variables (cm) yielded high areas under the tdROC curves (AUCs) for predicting survival (AUC 0.81-0.84) at 5 years after diagnosis and predicted outcome (hazard ratios [HRs] of 1.42-1.76, p < 0.001 for all). Only MAX

conclusionAmong all MRI-derived tumor size measurements, MAX

Indexed as

Cervical cancerDisease-specific survivalMRITumor size

Identifiers

PMID35715582
PMCPMC9206052
OpenAlexW4283027830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.