Evidence map›Paper›PMID 35715531›Full record

ArticleScientific reports2022

Image resampling and discretization effect on the estimate of myocardial radiomic features from T1 and T2 mapping in hypertrophic cardiomyopathy.

Daniela Marfisi, Carlo Tessa, Chiara Marzi, Jacopo Del Meglio, Stefania Linsalata, Rita Borgheresi, Alessio Lilli, Riccardo Lazzarini, Luca Salvatori, Claudio Vignali and 6 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

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  4. Insights into radiomics: a comprehensive review for beginners.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 1 country.

Daniela Marfisi *Unit of Medical Physics, Pisa University Hospital "Azienda Ospedaliero-Universitaria Pisana", Via Roma 67, 56126, Pisa, Italy.
Carlo Tessa *Unit of Radiology, Azienda USL Toscana Nord Ovest, Apuane Hospital, 54100, Massa, Italy.
Chiara MarziInstitute of Applied Physics "Nello Carrara", Italian National Research Council, 50019, Sesto Fiorentino, Italy.
Jacopo Del MeglioUnit of Cardiology, Azienda USL Toscana Nord Ovest, Versilia Hospital, 55041, Lido di Camaiore, Italy.
Stefania LinsalataUnit of Medical Physics, Pisa University Hospital "Azienda Ospedaliero-Universitaria Pisana", Via Roma 67, 56126, Pisa, Italy.
Rita BorgheresiUnit of Medical Physics, Pisa University Hospital "Azienda Ospedaliero-Universitaria Pisana", Via Roma 67, 56126, Pisa, Italy.
Alessio LilliUnit of Cardiology, Azienda USL Toscana Nord Ovest, Versilia Hospital, 55041, Lido di Camaiore, Italy.
Riccardo LazzariniUnit of Radiology, Azienda USL Toscana Nord Ovest, Versilia Hospital, 55041, Lido di Camaiore, Italy.
Luca SalvatoriUnit of Radiology, Azienda USL Toscana Nord Ovest, Versilia Hospital, 55041, Lido di Camaiore, Italy.
Claudio VignaliUnit of Radiology, Azienda USL Toscana Nord Ovest, Versilia Hospital, 55041, Lido di Camaiore, Italy.
Andrea BarucciInstitute of Applied Physics "Nello Carrara", Italian National Research Council, 50019, Sesto Fiorentino, Italy.
Mario MascalchiDepartment of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, 50121, Florence, Italy.
Giancarlo CasoloUnit of Cardiology, Azienda USL Toscana Nord Ovest, Versilia Hospital, 55041, Lido di Camaiore, Italy.
Stefano DiciottiDepartment of Electrical, Electronic, and Information Engineering "Guglielmo Marconi", University of Bologna, 47522, Cesena, Italy.
Antonio Claudio TrainoUnit of Medical Physics, Pisa University Hospital "Azienda Ospedaliero-Universitaria Pisana", Via Roma 67, 56126, Pisa, Italy.
Marco GiannelliUnit of Medical Physics, Pisa University Hospital "Azienda Ospedaliero-Universitaria Pisana", Via Roma 67, 56126, Pisa, Italy. m.giannelli@ao-pisa.toscana.it.
Ospedale Versilia · ITAzienda Ospedaliera Universitaria Pisana · ITAzienda Usl Toscana Centro · ITNational Research Council · ITNello Carrara Institute of Applied Physics · ITUniversity of Bologna · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiomics is emerging as a promising and useful tool in cardiac magnetic resonance (CMR) imaging applications. Accordingly, the purpose of this study was to investigate, for the first time, the effect of image resampling/discretization and filtering on radiomic features estimation from quantitative CMR T1 and T2 mapping. Specifically, T1 and T2 maps of 26 patients with hypertrophic cardiomyopathy (HCM) were used to estimate 98 radiomic features for 7 different resampling voxel sizes (at fixed bin width), 9 different bin widths (at fixed resampling voxel size), and 7 different spatial filters (at fixed resampling voxel size/bin width). While we found a remarkable dependence of myocardial radiomic features from T1 and T2 mapping on image filters, many radiomic features showed a limited sensitivity to resampling voxel size/bin width, in terms of intraclass correlation coefficient (> 0.75) and coefficient of variation (< 30%). The estimate of most textural radiomic features showed a linear significant (p < 0.05) correlation with resampling voxel size/bin width. Overall, radiomic features from T2 maps have proven to be less sensitive to image preprocessing than those from T1 maps, especially when varying bin width. Our results might corroborate the potential of radiomics from T1/T2 mapping in HCM and hopefully in other myocardial diseases.

Indexed as

Cardiomyopathy, HypertrophicHeartHumansImage Processing, Computer-AssistedMagnetic Resonance Imaging

Identifiers

PMID35715531
PMCPMC9205876
OpenAlexW4283028665

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.