Evidence map›Paper›PMID 35715142›Full record

ReviewSurgical oncology clinics of North America2022

Management of Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma.

Aimee M Crago, Kenneth Cardona, Hanna Koseła-Paterczyk, Piotr Rutkowski

Open access · greenAbstract readReview
In one paragraph

Review in Surgical oncology clinics of North America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Aimee M CragoDepartment of Surgery, Gastric and Mixed Tumor Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, H1220, New York, NY, USA. Electronic address: cragoa@mskcc.org.
Kenneth CardonaDivision of Surgical Oncology, Department of Surgery, Sarcoma Disease Team, Winship Cancer Institute, Emory University Hospital Midtown, Emory University School of Medicine, 550 Peachtree St, NEMOT, 9th floor, Atlanta, GA 30322, USA. Electronic address: https://twitter.com/@kencardonaMD.
Hanna Koseła-PaterczykMaria Sklodowska-Curie National Research Institute of Oncology, Deputy for Clinical Oncology Unit in Department of Soft Tissue/Bone, Sarcoma and Melanoma, Warsaw, Poland.
Piotr RutkowskiMaria Sklodowska-Curie National Research Institute of Oncology, Sarcoma and Melanoma, Roentgena 5, 02-781 Warszawa, Poland. Electronic address: https://twitter.com/@rutkowskip1972.
Emory University Hospital Midtown · USMemorial Sloan Kettering Cancer Center · USNational Institute of Oncology · HU

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Targeting Oncogenic Pathways in Genetically Complex SarcomasP50CA217694 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI William D. Tap · 2018 to 2026
$21.5M
NCI NIH HHS P30 CA008748NCI NIH HHS P50 CA217694
6 · The paper itself

Abstract

Undifferentiated pleomorphic sarcoma (UPS) and myxofibrosarcoma (MFS) are genomically complex tumors commonly diagnosed in the extremities or trunk of elderly patients. They likely represent a spectrum of disease differentiated by myxoid stroma and curvilinear vessels observed in MFS but not in UPS. Limb-sparing surgery is the standard of care although the infiltrative nature of MFS mandates wider resection margins than are necessary for UPS. UPS are conversely associated with high risks of distal recurrence, often prompting recommendations for adjuvant chemotherapy. In both histologies, anthracycline-based therapies or gemcitabine and docetaxel are used to manage advanced disease; immunotherapy may be of benefit in a subset of patients.

Indexed as

FibrosarcomaHistiocytoma, Malignant FibrousSarcomaSoft Tissue NeoplasmsAdultAgedExtremitiesHumansLimb-sparing surgeryMalignant fibrous histiocytomaMyxofibrosarcomaSoft tissue sarcomasystemic therapyUndifferentiated pleomorphic sarcoma

Identifiers

PMID35715142
PMCPMC11254341
OpenAlexW4282920042

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.