Evidence map›Paper›PMID 35714395›Full record

ArticleJournal of infection and public health2022

Neonatal outcomes related to maternal SARS-CoV-2 infection in French Guiana: A case-control study.

N Elenga, M-J Wandji, J Siban, M Nacher, M Demar

Open access · goldAbstract read
In one paragraph

Article in Journal of infection and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

N ElengaPediatric Unit, Centre Hospitalier de Cayenne, Rue des flamboyants, BP 6006, 97306 Cedex Cayenne, French Guiana; EA 3593, Faculty of Medicine, Université des Antilles et de la Guyane, Guadeloupe; Department of Gynecology and Obstetrics, Centre Hospitalier de Cayenne, Rue des flamboyants, BP 6006, 97306 Cedex Cayenne, French Guiana. Electronic address: elengafr@yahoo.fr.
M-J WandjiNeonatal Unit, Centre Hospitalier de Cayenne, Rue des flamboyants, BP 6006, 97306 Cedex Cayenne, French Guiana; Department of Gynecology and Obstetrics, Centre Hospitalier de Cayenne, Rue des flamboyants, BP 6006, 97306 Cedex Cayenne, French Guiana.
J SibanPediatric Unit, Centre Hospitalier de Cayenne, Rue des flamboyants, BP 6006, 97306 Cedex Cayenne, French Guiana; EA 3593, Faculty of Medicine, Université des Antilles et de la Guyane, Guadeloupe; Neonatal Unit, Centre Hospitalier de Cayenne, Rue des flamboyants, BP 6006, 97306 Cedex Cayenne, French Guiana; Department of Gynecology and Obstetrics, Centre Hospitalier de Cayenne, Rue des flamboyants, BP 6006, 97306 Cedex Cayenne, French Guiana; Centre d'Investigation Clinique Antilles-Guyane, Inserm 1424, Centre Hospitalier de Cayenne, Rue des flamboyants, BP 6006, 97306 Cedex Cayenne, French Guiana; Parasitology-Mycology, EA 3593, Faculty of Medicine, Université des Antilles et de la Guyane, Guadeloupe.
M NacherDepartment of Gynecology and Obstetrics, Centre Hospitalier de Cayenne, Rue des flamboyants, BP 6006, 97306 Cedex Cayenne, French Guiana; Centre d'Investigation Clinique Antilles-Guyane, Inserm 1424, Centre Hospitalier de Cayenne, Rue des flamboyants, BP 6006, 97306 Cedex Cayenne, French Guiana.
M DemarEA 3593, Faculty of Medicine, Université des Antilles et de la Guyane, Guadeloupe; Department of Gynecology and Obstetrics, Centre Hospitalier de Cayenne, Rue des flamboyants, BP 6006, 97306 Cedex Cayenne, French Guiana; Parasitology-Mycology, EA 3593, Faculty of Medicine, Université des Antilles et de la Guyane, Guadeloupe.
Centre Hospitalier Andrée Rosemon · GFUniversité des Antilles · GP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aims to assess the neonatal outcomes related to maternal SARS-COV-2 infection.

methodsIn this study, we identified newborns born between May 14 and August 31, 2020, to mothers who were PCR-SRAS-CoV-2 positive at the time of delivery. From the cohort of 974 infants, we performed a nested case-control study.

resultsDuring the study period, 133 (13.7%) mothers were positive for SARS-CoV-2. Among the 35 pregnant women with COVID-19 symptoms (26.3%), cough was the most common symptom, present in half of the cases. Four of them have progressed to critical pneumonia requiring transfer to intensive care unit. The neonates from mothers with positive SARS-CoV-2-RT-PCR, were routinely tested for COVID-19 within the first 24 h after labor, and 3 other newborns tested in the presence of symptoms. There was no significant difference between the two groups with respect to preterm birth, meconium-stained amniotic fluid distress, and neonatal asphyxia. Most infants were breastfed at birth, regardless of their mothers' COVID-19 status. In COVID-19-positive pregnant women admitted to intensive care unit, the proportion of preterm births (OR=12.5 [1.7-90.5]), fetal death in utero (OR=25.9 [2.2-305]) and admission in neonatal intensive care unit admission (OR=13.4 [3.0-60]), appeared higher than the controls. No maternal deaths were recorded.

conclusionsOur data suggest little neonatal morbidity associated with maternal COVID-19, except for those born to mothers admitted to intensive care unit. However, under breastfeeding conditions with rigorous hygiene precautions and parental education, the risk of transmission of SARS-COV-2 virus to the newborn was very low.

Indexed as

COVID-19Pregnancy Complications, InfectiousPremature BirthCase-Control StudiesFemaleFrench GuianaHumansInfantInfant, NewbornInfectious Disease Transmission, VerticalPregnancyPregnancy OutcomeSARS-CoV-2BreastfeedingLow riskMild infectionNewbornSARS-COV-2 positive mother

Identifiers

PMID35714395
PMCPMC9190176
OpenAlexW4282558662

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.