Evidence map›Paper›PMID 35714271›Full record

ReviewHuman vaccines & immunotherapeutics2022

Adenovirus vector-based vaccines as forefront approaches in fighting the battle against flaviviruses.

Mohammad Shoushtari, Farzin Roohvand, Mostafa Salehi-Vaziri, Arash Arashkia, Hasan Bakhshi, Kayhan Azadmanesh

Open access · goldAbstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

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  11. A review on Zika vaccine development.Pathogens and disease · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mohammad ShoushtariDepartment of Molecular Virology, Pasteur Institute of Iran, Tehran, Iran.
Farzin RoohvandDepartment of Molecular Virology, Pasteur Institute of Iran, Tehran, Iran.
Mostafa Salehi-VaziriDepartment of Arboviruses and Viral Hemorrhagic Fevers (National Reference Laboratory), Pasteur Institute of Iran, Tehran, Iran.
Arash ArashkiaDepartment of Molecular Virology, Pasteur Institute of Iran, Tehran, Iran.
Hasan BakhshiMalaria and Vector Research Group (MVRG), Biotechnology Research Center (BRC), Pasteur Institute of Iran, Tehran, Iran.
Kayhan AzadmaneshDepartment of Molecular Virology, Pasteur Institute of Iran, Tehran, Iran.
Pasteur Institute of Iran · IRBiotechnology Research Center · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flaviviruses are arthropod-borne viruses (arboviruses) that have been recently considered among the significant public health problems in defined geographical regions. In this line, there have been vaccines approved for some flaviviruses including dengue virus (DENV), Japanese encephalitis virus (JEV), yellow fever virus (YFV), and tick-borne encephalitis virus (TBEV), although the efficiency of such vaccines thought to be questionable. Surprisingly, there are no effective vaccine for many other hazardous flaviviruses, including West Nile and Zika viruses. Furthermore, in spite of approved vaccines for some flaviviruses, for example DENV, alternative prophylactic vaccines seem to be still needed for the protection of a broader population, and it originates from the unsatisfying safety, and the efficacy of vaccines that have been introduced. Thus, adenovirus vector-based vaccine candidates are suggested to be effective, safe, and reliable. Interestingly, recent widespread use of adenovirus vector-based vaccines for the COVID-19 pandemic have highlighted the importance and feasibility of their widespread application. In this review, the applicability of adenovirus vector-based vaccines, as promising approaches to harness the diseases caused by Flaviviruses, is discussed.

Indexed as

Adenovirus VaccinesCOVID-19Dengue VirusEncephalitis Viruses, Tick-BorneZika VirusZika Virus InfectionAdenoviridaeCOVID-19 VaccinesHumansAdenovirus VaccinesCOVID-19 VaccinesAdenovirusarbovirusFlavivirusvaccinevector-borne diseases

Identifiers

PMID35714271
PMCPMC9481145
OpenAlexW4283028828

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.