ArticleJournal of general internal medicine2022
A Chronic Condition Disguised as an Acute Event: the Case for Re-thinking Stimulant Overdose Death.
Article in Journal of general internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 22 citations in OpenAlex.
- Unwanted effects, self-management strategies, and consequences of unwanted effects of methamphetamine use.Drug and alcohol dependence · 2026Article
- Cardiovascular Conditions and Symptoms in Deaths Attributed to Acute Stimulant Toxicity.Circulation. Population health and outcomes · 2026Article
- Associations Between Sustained Methamphetamine/Amphetamine Use and Left Ventricular Dysfunction in a Cohort of Women Living With and Without HIV.Journal of the American Heart Association · 2026Article
- Antecedents of Fentanyl Coinvolvement in Deaths Attributed to Stimulant Poisoning in San Francisco, CA.Journal of addiction medicine · 2026Article
- Thematic analysis of medical examiner narratives to understand the socio-spatial context, recency of drug use, and likely mechanism of stimulant toxicity deaths.Drug and alcohol dependence · 2025Article
- Prevalence of adults with stimulant misuse and/or stimulant use disorder in Massachusetts, USA, 2014-2021.Addiction (Abingdon, England) · 2025Article
- Prevalence of stimulant use and the role of opioid agonist treatment among people who inject drugs in France: Results from the COSINUS cohort study.Drug and alcohol review · 2025Article
- Naloxone administration and survival in overdoses involving opioids and stimulants: An analysis of law enforcement data from 63 Pennsylvania counties.The International journal on drug policy · 2025Article
- Managing Stimulant Use Among People With HIV: Harm-Reduction Strategies From Behavior to Medication.Topics in antiviral medicine · 2024Review
- Chronic disease diagnoses and health service use among people who died of illicit drug toxicity in British Columbia, Canada.BMC medicine · 2024Article
- Naloxone Administration and Survival in Overdoses Involving Opioids and Stimulants: An Analysis of Law Enforcement Data from 63 Pennsylvania Counties.medRxiv : the preprint server for health sciences · 2024Article
- Safety strategies and harm reduction for methamphetamine users in the era of fentanyl contamination: A qualitative analysis.The International journal on drug policy · 2024Article
- Accidental substance-related acute toxicity deaths in older adults in 2016 and 2017: a national chart review study.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2024Article
- Presentation and Outcomes of Adults With Overdose-Related Out-of-Hospital Cardiac Arrest.JAMA network open · 2023Article
- A qualitative study of interest in and preferences for potential medications to treat methamphetamine use disorder.Addiction science & clinical practice · 2023Article
- Multiple substance use and blood pressure in women experiencing homelessness.Addictive behaviors reports · 2023Article
- Association of Opioid and Stimulant Use Disorder Diagnoses With Fatal and Nonfatal Overdose Among People With a History of Incarceration.JAMA network open · 2022Article
- Stimulant-Involved Cardiovascular Disease Mortality and Life Years Lost, 2014 to 2023.Substance use : research and treatmentArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Recent reports indicate that stimulant-related deaths are increasing dramatically. People who die from acute stimulant toxicity have high rates of pre-existing cardiovascular disease (CVD), much of which is undiagnosed. Moreover, people who use stimulants with CVD often remain asymptomatic until presenting to an emergency department with an acute event. Prior research shows that symptoms of stimulant toxicity may occur on a regular basis, and that people who die from stimulant toxicity are older than those who die of opioid toxicity. Taken collectively, the existing evidence suggests that death from acute stimulant toxicity is often an outcome of long-term, cumulative exposure leading to cardiovascular dysfunction rather than acute intoxication. Strategies tailored to the distinct etiology of stimulant overdose are needed. We propose a three-part approach including (1) implementing stimulant use interventions that promote not only abstinence, but also use reduction, (2) treating ongoing stimulant use as a chronic cardiovascular condition, and (3) making stimulant toxicity interventions relevant to the populations most affected, which includes people outside of the traditional health-care system. In short, to reduce stimulant-related fatality, we need to transform our approach in ways that are tailored to address its natural history.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.