ReviewCurrent neurology and neuroscience reports2022
Surgical Treatment of Drug-Resistant Generalized Epilepsy.
Review in Current neurology and neuroscience reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- An examination of seizure-free outcome and visual field deficits: Anterior temporal lobectomy versus selective amygdalohippocampectomy for temporal lobe epilepsy-a systematic review and meta-analysis for comprehensive understanding.Acta neurochirurgica · 2024Pooled it
- Peripheral blood inflammatory biomarkers and response to vagus nerve stimulation in pediatric drug-resistant epilepsy: A retrospective cohort study.European journal of pediatrics · 2026Article
- Article
- MRgLITT under general anesthesia using extended non-ferromagnetic components in a non-MR-compatible environment-a case report.BMC anesthesiology · 2026Article
- Chronic thalamic recordings for idiopathic generalized epilepsy and Lennox-Gastaut syndrome: Ictal and interictal electrophysiological findings.Epilepsia open · 2025Article
- Perioperative Management of Patients With Seizure Disorders: Part I.Anesthesia progress · 2025Review
- SRF Facilitates Transcriptional Inhibition of Gem Expression by m6A Methyltransferase METTL3 to Suppress Neuronal Damage in Epilepsy.Molecular neurobiology · 2025Article
- Compound 350: A New Hope for Individuals with Drug-resistant Epilepsy.Annals of neurosciences · 2024Article
- Clinical features of 21 cases of drug-resistant epilepsy and the therapeutic effect of stereotactic electroencephalography guided epileptic foci resection.American journal of translational research · 2024Article
- Therapeutic approaches targeting seizure networks.Frontiers in network physiology · 2024Review
- Neurostimulation for Generalized Epilepsy: Should Therapy be Syndrome-specific?Neurosurgery clinics of North America · 2024Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewTo summarize current evidence and recent developments in the surgical treatment of drug-resistant generalized epilepsy. RECENT
findingsCurrent surgical treatments of drug-resistant generalized epilepsy include vagus nerve stimulation (VNS), deep brain stimulation (DBS) and corpus callosotomy (CC). Neurostimulation with VNS and/or DBS has been shown to be effective in reducing seizure frequency in patients with generalized epilepsy. DBS for generalized epilepsy is primarily consisted of open-loop stimulation directed at the centromedian (CM) nucleus in the thalamus, though closed-loop stimulation and additional targets are being explored. CC can be effective in treating some seizure types and can be performed using traditional surgical techniques or with the less invasive methods of laser ablation and radiosurgery. This current literature supports the use of VNS, DBS and CC, alone or in combination, as palliative treatments of drug-resistant generalized epilepsy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.