Evidence map›Paper›PMID 35713660›Full record

ArticleCalcified tissue international2022

Is Regular Weight-Bearing Physical Activity Throughout the Lifecourse Associated with Better Bone Health in Late Adulthood?

Jean Zhang, Camille Parsons, Nicholas Fuggle, Kate A Ward, Cyrus Cooper, Elaine Dennison

Open access · hybridAbstract read
In one paragraph

Article in Calcified tissue international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Association of physical activity with fracture: a prospective cohort study of 387,307 Chinese participants.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Early Life Programming of Skeletal Health.Current osteoporosis reports · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Jean ZhangMRC Lifecourse Epidemiology Centre Southampton General Hospital, Tremona Rd, Southampton, SO16 6YD, UK.ORCID 0000-0001-7589-9805
Camille ParsonsMRC Lifecourse Epidemiology Centre Southampton General Hospital, Tremona Rd, Southampton, SO16 6YD, UK.
Nicholas FuggleMRC Lifecourse Epidemiology Centre Southampton General Hospital, Tremona Rd, Southampton, SO16 6YD, UK.
Kate A WardMRC Lifecourse Epidemiology Centre Southampton General Hospital, Tremona Rd, Southampton, SO16 6YD, UK.ORCID 0000-0001-7034-6750
Cyrus CooperMRC Lifecourse Epidemiology Centre Southampton General Hospital, Tremona Rd, Southampton, SO16 6YD, UK.
Elaine DennisonMRC Lifecourse Epidemiology Centre Southampton General Hospital, Tremona Rd, Southampton, SO16 6YD, UK. emd@mrc.soton.ac.uk.
Southampton General Hospital · GB

Funding

Medical Research Council G0400491Medical Research Council MC_PC_21000Medical Research Council MC_PC_21001Medical Research Council MC_PC_21003Medical Research Council MC_PC_21022Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Medical Research Council MC_UP_A620_1014Medical Research Council MC_UP_A620_1015Medical Research Council MC_UU_12011/1Medical Research Council MC_UU_12011/2Versus Arthritis 19583
6 · The paper itself

Abstract

We considered how weight-bearing physical activity (WBPA) through the lifecourse related to bone health in late adulthood in the Hertfordshire Cohort Study (HCS), a cohort of community dwelling adults born 1931-9, to identify sex-specific differences and periods critical for optimal bone health. Available questionnaire data from 258 participants (128 men and 130 women) included current reported lifestyle factors (including physical activity) and WBPA, coded as participation in WBPA aged < 18 years; aged 18-29 years; aged 30-49 years and aged ≥ 50 years. Responses were recorded as none/once a month/once a week/> once a week. Hip bone mineral density (BMD) was measured using a Lunar Prodigy DXA scanner. The mean age was 75.4 (SD 2.5) years in men and 75.7 (SD 2.6) years in women. Men reported significantly higher levels of past WBPA aged < 18 years (p = 0.006) and aged 18-29 years than women (p < 0.001). We observed greater BMD at total hip in women who reported regular WBPA at ages 18-29 years (p = 0.02) and 30-49 years (p = 0.02) compared with those who reported no WBPA (p = 0.019), after adjustment for confounders including current activity levels. In this cohort of older adults, recalled regular WBPA around the time of peak bone mass acquisition was less common in women than men, but associated with higher hip BMD in women in late adulthood.

Indexed as

Bone and BonesBone DensityAdultAgedCohort StudiesExerciseFemaleHumansMaleWeight-BearingBMDLifecoursePhysical activityWeight bearing

Identifiers

PMID35713660
PMCPMC9395437
OpenAlexW4283019276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.