Evidence map›Paper›PMID 35713469›Full record

ArticleAngewandte Chemie (International ed. in English)2022

BTDAzo: A Photoswitchable TRPC5 Channel Activator.

Markus Müller, Konstantin Niemeyer, Nicole Urban, Navin K Ojha, Frank Zufall, Trese Leinders-Zufall, Michael Schaefer, Oliver Thorn-Seshold

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Impact of C-Terminal PKC Phosphorylation on TRPC6 Current Kinetics.International journal of molecular sciences · 2025
    Article
  3. Review
  4. Article
  5. Detour to success: photoswitchingChemical science · 2024
    Review
  6. BTDAzo: A Photoswitchable TRPC5 Channel Activator.Angewandte Chemie (International ed. in English) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Markus MüllerDepartment of Pharmacy, LMU Munich, Butenandtstrasse 7, 81377, Munich, Germany.
Konstantin NiemeyerRudolf-Boehm-Institute of Pharmacology and Toxicology, Leipzig University, Härtelstraße 16-18, 04107, Leipzig, Germany.
Nicole UrbanRudolf-Boehm-Institute of Pharmacology and Toxicology, Leipzig University, Härtelstraße 16-18, 04107, Leipzig, Germany.
Navin K OjhaCenter for Integrative Physiology and Molecular Medicine, Saarland University, Kirrbergerstraße 100, 66421, Homburg, Germany.
Frank ZufallCenter for Integrative Physiology and Molecular Medicine, Saarland University, Kirrbergerstraße 100, 66421, Homburg, Germany.
Trese Leinders-ZufallCenter for Integrative Physiology and Molecular Medicine, Saarland University, Kirrbergerstraße 100, 66421, Homburg, Germany.
Michael SchaeferRudolf-Boehm-Institute of Pharmacology and Toxicology, Leipzig University, Härtelstraße 16-18, 04107, Leipzig, Germany.
Oliver Thorn-SesholdDepartment of Pharmacy, LMU Munich, Butenandtstrasse 7, 81377, Munich, Germany.ORCID 0000-0003-3981-651X
Leipzig University · DESaarland University · DELMU Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photoswitchable reagents can be powerful tools for high-precision biological control. TRPC5 is a Ca

Indexed as

NeuronsTRPC Cation ChannelsAnimalsCalciumMiceCalciumTrpc5 protein, mouseTRPC Cation ChannelsAgonistsCation ChannelsLigand DesignPhotopharmacologyProlactin Signaling

Identifiers

PMID35713469
PMCPMC9542918
OpenAlexW4283015134

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.