Evidence map›Paper›PMID 35713359›Full record

ArticleMagnetic resonance in medicine2022

Deep-learning synthesized pseudo-CT for MR high-resolution pediatric cranial bone imaging (MR-HiPCB).

Parna Eshraghi Boroojeni, Yasheng Chen, Paul K Commean, Cihat Eldeniz, Gary B Skolnick, Corinne Merrill, Kamlesh B Patel, Hongyu An

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Parna Eshraghi BoroojeniDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri.ORCID 0000-0002-4996-2601
Yasheng ChenDepartment of Neurology, Washington University in St. Louis, St. Louis, Missouri.
Paul K CommeanMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri.
Cihat EldenizMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri.ORCID 0000-0002-4457-0916
Gary B SkolnickDivision of Plastic and Reconstructive Surgery, Washington University in St. Louis, St. Louis, Missouri.
Corinne MerrillDivision of Plastic and Reconstructive Surgery, Washington University in St. Louis, St. Louis, Missouri.
Kamlesh B PatelDivision of Plastic and Reconstructive Surgery, Washington University in St. Louis, St. Louis, Missouri.
Hongyu AnDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri.ORCID 0000-0001-6459-2269
Washington University in St. Louis · USMallinckrodt (United States) · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Robust and Rapid 3D High-Resolution Cranial bone imaging for pediatric patients using MRIR01EB032713 · NIBIB · WASHINGTON UNIVERSITY · PI AN, HONGYU, PATEL, KAMLESH · 2022 to 2025
$2.5M
NCATS NIH HHS UL1 TR002345NIBIB NIH HHS R01 EB032713
6 · The paper itself

Abstract

purposeCT is routinely used to detect cranial abnormalities in pediatric patients with head trauma or craniosynostosis. This study aimed to develop a deep learning method to synthesize pseudo-CT (pCT) images for MR high-resolution pediatric cranial bone imaging to eliminating ionizing radiation from CT.

methods3D golden-angle stack-of-stars MRI were obtained from 44 pediatric participants. Two patch-based residual UNets were trained using paired MR and CT patches randomly selected from the whole head (NetWH) or in the vicinity of bone, fractures/sutures, or air (NetBA) to synthesize pCT. A third residual UNet was trained to generate a binary brain mask using only MRI. The pCT images from NetWH (pCT

resultspCT

conclusionMR high-resolution pediatric cranial bone imaging may facilitate the clinical translation of a radiation-free MR cranial bone imaging method for pediatric patients.

Indexed as

Deep LearningImage Processing, Computer-AssistedChildHumansMagnetic Resonance ImagingSkullTomography, X-Ray Computedcranial bone imagingcraniosynostosisdeep learninghead traumaMRIpseudo-CT

Identifiers

PMID35713359
PMCPMC9420780
OpenAlexW4283020645

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.