Evidence map›Paper›PMID 35712963›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

Combined CSF-venous Fistula and middle meningeal artery embolization for treatment of spontaneous intracranial hypotension.

Ajay A Madhavan, Jeremy K Cutsforth-Gregory, Soliman H Oushy, Nicholas Borg, Waleed Brinjikji

Open access · greenAbstract readCase Reports
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Rescue management of recurrent or growing non-acute subdural hematoma following standalone or adjunctive middle meningeal artery embolization: A case series and systematic review.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ajay A MadhavanDivision of Neuroradiology, Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.ORCID 0000-0003-1794-4502
Jeremy K Cutsforth-GregoryDepartment of Neurology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.
Soliman H OushyDepartment of Neurosurgery, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.ORCID 0000-0001-6343-6950
Nicholas BorgDepartment of Neurosurgery, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.ORCID 0000-0001-6291-9061
Waleed BrinjikjiDivision of Neuroradiology, Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.
Mayo Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transvenous Onyx embolization was recently described as an effective treatment of spontaneous intracranial hypotension caused by CSF-venous fistulas. Patients with CSF-venous fistulas can present with a wide spectrum of clinical and imaging findings, sometimes including spontaneous subdural hematomas, subdural hygromas, or a combination of both. Here, we describe four patients with spontaneous intracranial hypotension complicated by subdural fluid collections caused by CSF-venous fistulas. The patients were treated with transvenous Onyx embolization of their CSF-venous fistulas and transarterial particle embolization of the bilateral middle meningeal arteries, with both procedures performed in a single treatment session. All four patients had clinical improvement and decreased size or resolution of their subdural fluid collections. Based on our findings, we believe that middle meningeal embolization could be a useful adjunct to CSF-venous fistula embolization. A case-control study comparing patients who did or did not undergo middle meningeal embolization will be necessary to validate this supposition.

Indexed as

Embolization, TherapeuticIntracranial HypotensionMeningeal ArteriesAdultAgedCerebral AngiographyDimethyl SulfoxideFemaleHumansMaleMiddle AgedPolyvinylsDimethyl SulfoxidePolyvinylsCSF leakCSF-venous fistulaembolizationSpontaneous intracranial hypotensionsubdural hematoma

Identifiers

PMID35712963
PMCPMC12202942
OpenAlexW4283011739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.