ArticleJournal of community hospital internal medicine perspectives2022
Extranodal Rosai-Dorfman Disease- a Review of Diagnostic Testing and Management.
Article in Journal of community hospital internal medicine perspectives, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Extranodal Rosai-Dorfman disease with bilateral renal involvement: A diagnostic challenge.Radiology case reports · 2026Article
- Rare presentation of Rosai-Dorfman disease with severe lymphopenia: a pediatric case report and review of the literature.Journal of cancer research and clinical oncology · 2026Review
- Facial Cutaneous Rosai-Dorfman Disease Misdiagnosed as Sporotrichosis: A Case Report and Literature Review.Clinical, cosmetic and investigational dermatology · 2026Article
- Rare Rosai-Dorfman disease presenting with basal ganglia and bilateral cerebral peduncles-diagnosis and challenges.Quantitative imaging in medicine and surgery · 2025Article
- Extranodal Rosai-Dorfman Disease in a Pediatric Patient: A Case Report.The American journal of case reports · 2025Article
- Respiratory tract involvement in Rosai-Dorfman disease - A report of two distinct cases.Heliyon · 2025Article
- Extranodal Rosai-Dorfman Disease of Breast Mimicker of Breast Malignancy.World journal of nuclear medicine · 2024Article
- Recurrent Soft Tissue Rosai Dorfman Disease of Right Medial Thigh Lipoma With Lymph Node Involvement.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2024Article
- Uncommon presentation of Rosai-Dorfman disease: Nasal and nasopharyngeal involvement: A case report and discussion.Radiology case reports · 2024Article
- Spontaneous Regression of Rosai-Dorfman Disease Presenting as a Thigh Mass With Vascular Involvement: A Case Report.Journal of investigative medicine high impact case reportsArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rosai-Dorfman disease (RDD) is a rare, benign histiocytic proliferative disorder primarily occurring in the lymph nodes. Extranodal disease can occur in skin and soft tissue, central nervous system, gastrointestinal tract, and breast. Here we present a case of a 55-year-old female with a history of hypertension, hyperlipidemia, and diabetes mellitus who presented with a fixed solid mass localized to the right medial thigh. Excision revealed S100 and CD 68 positive scattered lymphoid aggregates and emperipolesis, hallmark molecular and cytopathologic features of RDD. RDD is a nonmalignant, classically sporadic histiocytosis. Clinical outcome in terms of mortality seems to be favorable in most cases, however given the benign and slowly progressive nature of the disease, conservative management with observation is typical, with surgical excision recommended for larger lesions. Currently, therapy revolves around surgical and immunosuppressive treatments, but the optimal diagnostic and therapeutic management of RDD remains to be defined.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.