Evidence map›Paper›PMID 35712365›Full record

ArticleData in brief2022

A dataset on patient-individual lymph node involvement in oropharyngeal squamous cell carcinoma.

Roman Ludwig, Jean-Marc Hoffmann, Bertrand Pouymayou, Grégoire Morand, Martina Broglie Däppen, Matthias Guckenberger, Vincent Grégoire, Panagiotis Balermpas, Jan Unkelbach

Abstract read
In one paragraph

Article in Data in brief, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Roman LudwigDepartement of Radiation Oncology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, CH.
Jean-Marc HoffmannDepartement of Radiation Oncology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, CH.
Bertrand PouymayouDepartement of Radiation Oncology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, CH.
Grégoire MorandHead and Neck Tumor Center, Comprehensive Cancer Center Zurich, Rämistrasse 100, 8091, Zurich, CH.
Martina Broglie DäppenHead and Neck Tumor Center, Comprehensive Cancer Center Zurich, Rämistrasse 100, 8091, Zurich, CH.
Matthias GuckenbergerDepartement of Radiation Oncology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, CH.
Vincent GrégoireRadiation Oncology Departement, Centre Léon Bérard, 28 Rue Laennec, 69008, Lyon, FR.
Panagiotis BalermpasDepartement of Radiation Oncology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, CH.
Jan UnkelbachDepartement of Radiation Oncology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, CH.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dataset: We provide a dataset on lymph node level (LNL) involvement in 287 patients with newly diagnosed oropharyngeal squamous cell carcinoma (OPSCC). For each patient, ipsilateral and contralateral LNL involvement for levels I to VII is reported together with clinicopathological factors including TNM-stage, primary tumor subsite, tumor lateralization, HPV status, sex, age, smoking status, and primary treatment. LNL involvement was assessed individually based on available diagnostic modalities (PET, MRI, CT, fine needle aspiration) by reviewing pathology and radiology reports together with the radiological images. The data is shared as a CSV-table with rows of patients and columns of patient/tumor-specific information and the involvement of individual LNL based on the respective diagnostic modalities. Reuse potential: Patterns of lymphatic progression have never been reported on a patient-individual basis in as much detail as provided in this dataset. The data can be used to build quantitative models for lymphatic tumor progression to estimate the probability of occult metastases in LNLs. This may in turn allow for further personalization of the elective clinical target volume definition in radiotherapy and the extent of neck dissection for surgically treated patients. The data can be pooled with other data to build large multi-institutional datasets on lymphatic metastatic progression in the future. Co-submission: This paper supports the original scientific article by Roman Ludwig, Jean-Marc Hoffmann, Bertrand Pouymayou, Grégoire Morand, Martina Broglie Däppen, Matthias Guckenberger, Vincent Grégoire, Panagiotis Balermpas, Jan Unkelbach, "Detailed patient-individual reporting of lymph node involvement in oropharyngeal squamous cell carcinoma with an online interface", Radiotherapy & Oncology [1].

Indexed as

Head & neck squamous cell carcinomaInterfaceLymphatic involvementOropharynxPatterns of progression

Identifiers

PMID35712365
PMCPMC9194687

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.