Evidence map›Paper›PMID 35712114›Full record

ReviewFrontiers in medicine2022

Comparison of COVID-19 Induced Respiratory Failure and Typical ARDS: Similarities and Differences.

Sen Lu, Xiaobo Huang, Rongan Liu, Yunping Lan, Yu Lei, Fan Zeng, Xuemei Tang, Hongli He

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sen LuDepartment of Intensive Care Unit, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Sichuan Provincial Key Laboratory for Human Disease Gene Study, Chengdu, China.
Xiaobo HuangDepartment of Intensive Care Unit, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Sichuan Provincial Key Laboratory for Human Disease Gene Study, Chengdu, China.
Rongan LiuDepartment of Intensive Care Unit, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Sichuan Provincial Key Laboratory for Human Disease Gene Study, Chengdu, China.
Yunping LanDepartment of Intensive Care Unit, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Sichuan Provincial Key Laboratory for Human Disease Gene Study, Chengdu, China.
Yu LeiDepartment of Intensive Care Unit, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Sichuan Provincial Key Laboratory for Human Disease Gene Study, Chengdu, China.
Fan ZengDepartment of Intensive Care Unit, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Sichuan Provincial Key Laboratory for Human Disease Gene Study, Chengdu, China.
Xuemei TangDepartment of Intensive Care Unit, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Sichuan Provincial Key Laboratory for Human Disease Gene Study, Chengdu, China.
Hongli HeDepartment of Intensive Care Unit, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Sichuan Provincial Key Laboratory for Human Disease Gene Study, Chengdu, China.
University of Electronic Science and Technology of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is a predominantly respiratory infectious disease caused by novel coronavirus infection (SARS-CoV-2), respiratory failure is the main clinical manifestation and the leading cause of death. Even though it can meet the acute respiratory distress syndrome (ARDS) Berlin definition, only some clinical features of COVID-19 are consistent with typical ARDS, and which has its own peculiar phenotypes. When compared with typical ARDS, in addition to the typical diffuse alveolar injury, COVID-19 has unique pathological and pathophysiological features, such as endothelial injury, extensive microthrombus, and pulmonary capillary hyperplasia. The clinical features of patients with respiratory failure caused by COVID-19 are heterogeneous and can be generally divided into two phenotypes: progressive respiratory distress and unique "silent hypoxemia". The "H-type" characteristics of reduced lung volume, decreased lung compliance, and unmatched ventilator-perfusion ratio. While some patients may have close to normal lung compliance, that is "L-type". Identifying the exact phenotype in whom are suffered with COVID-19 is crucial to guide clinicians to adopt appropriate treatment strategies. This review discussed the similarities and differences in the pathogenesis, pathophysiology, clinical features and treatment strategies of COVID-19 induced acute respiratory failure and typical ARDS.

Indexed as

ARDSCOVID-19pathogenesispathophysiologytreatment

Identifiers

PMID35712114
PMCPMC9196311
OpenAlexW4281784391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.