Evidence map›Paper›PMID 35712006›Full record

ArticleComputational and mathematical methods in medicine2022

Quantitative Data Integration Analysis Method for Cross-Studies: Obstructive Sleep Apnea as an Example.

Rong Zhou, Shengrong Zhou, Qiguang Xia, Tiejun Zhang, Guoqing Zhang

Abstract read
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Rong ZhouDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai 200232, China.ORCID https://orcid.org/0000-0001-7637-6547
Shengrong ZhouHuman Phenome Institute, School of Life Sciences, Fudan University, Shanghai 200232, China.ORCID https://orcid.org/0000-0002-0190-877X
Qiguang XiaCAS Key Laboratory of Computational Biology, Bio-Med Big Data Center, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Science, Shanghai 200031, China.ORCID https://orcid.org/0000-0001-7248-0822
Tiejun ZhangDepartment of Epidemiology, School of Public Health, Fudan University, Shanghai 200232, China.ORCID https://orcid.org/0000-0002-5187-7393
Guoqing ZhangCAS Key Laboratory of Computational Biology, Bio-Med Big Data Center, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Science, Shanghai 200031, China.ORCID https://orcid.org/0000-0001-8827-7546

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: In recent years, the prevalence of obstructive sleep apnea (OSA) has gradually increased. The diagnosis of this multiphenotypic disorder requires a combination of several indicators. The objective of this study was to find significant apnea monitor indicators of OSA by developing a strategy for cross-study screening and integration of quantitative data. Methods: Articles related to sleep disorders were obtained from the PubMed database. A sleep disorder dataset and an OSA dataset were manually curated from these articles. Two evaluation indexes, the indicator coverage ratio (ICR) and the study integrity ratio (SIR), were used to filter out OSA indicators from the OSA dataset and create profiles including different numbers of indicators and studies for analysis. Data were analyzed by the Results: The sleep disorder dataset was constructed based on 178 studies from 119 publications, the OSA dataset was extracted from 89 studies, 284 sleep-related indicators were filtered out, and 22 profiles were constructed. Apnea hypopnea index was significantly decreased in all 22 profiles. Total sleep time (TST) (min) showed no significant differences in 21 profiles. There were significant increases in rapid eye movement (REM) (%TST) in 18 profiles, minimum arterial oxygen saturation (SaO Conclusion: The proposed data integration strategy successfully identified multiple significant OSA indicators.

Indexed as

Sleep Apnea, ObstructiveHumansPolysomnographyResearch DesignSleepSleep, REM

Identifiers

PMID35712006
PMCPMC9197656

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.