ReviewJournal of community hospital internal medicine perspectives2022
Acute Esophageal Necrosis: An In-depth Review of Pathogenesis, Diagnosis and Management.
Review in Journal of community hospital internal medicine perspectives, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Acute esophageal necrosis in patients with diabetic ketoacidosis: a systematic review of clinical features and outcomes.Clinical journal of gastroenterology · 2026Pooled it
- Markers of Prognosis for Acute Esophageal Necrosis: A Systematic Review.Digestive diseases (Basel, Switzerland) · 2025Pooled it
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- Acute oesophageal necrosis: single centre experience.BMC gastroenterology · 2026Article
- When Hyperglycemia Turns Black: Acute Necrotizing Esophagitis in a Catastrophic Metabolic Crisis: A Case Report.Life (Basel, Switzerland) · 2026Article
- Case report: Three contrasting presentations of acute oesophageal necrosis and the determinants of outcome.Frontiers in medicine · 2026Article
- A Case of Black Esophagus in a Patient Presenting With Dyspnea.The Korean journal of helicobacter and upper gastrointestinal research · 2025Article
- Multidisciplinary Management of Acute Esophageal Necrosis Secondary to Alcoholic Lactic Acidosis: A Case Report.Reports (MDPI) · 2025Article
- Multidisciplinary Management of a Patient with acute Oesophageal Necrosis and Severe Neurological Symptoms with Full Recovery.European journal of case reports in internal medicine · 2025Article
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- Microvascular cutaneous flap for treatment of complications of black esophagus and complex esophageal reconstruction.JTCVS techniques · 2023Article
- A View in the Dark: Two Cases of Acute Esophageal Necrosis in the Setting of Diabetic Ketoacidosis.Journal of investigative medicine high impact case reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Acute esophageal necrosis (AEN) is an uncommon but fatal cause of upper gastrointestinal bleeding. The complex pathophysiology of the disorder provides multiple points for intervention. Therefore, it is important to discuss the many multifaceted aspects of the disease. Methods: A scoping review was performed using PubMed, Google Scholar, and ClinicalTrials.gov. We reviewed literature from 1990 to 2021. The keywords used were 'acute esophageal necrosis', 'upper GI bleed', 'pathogenesis', 'EGD', 'prognosis'. Results and conclusions: The review summarized findings of 46 studies. AEN usually targets older males who have underlying cardiovascular disease. The middle part of the esophagus is commonly involved. The pathogenesis of AEN depends on conditions that increase risk of mucosal damage such as ischemia, lack of mucosal protection and excessive gastric reflux. Some medications are also responsible for the disease. Esophagogastroduodenoscopy is usually the gold standard for diagnosis. Findings suggestive of AEN include darkened, sharply demarcated circumferential areas. Supportive measures, including bowel rest, fluid supplementation and proton pump inhibitors are the cornerstone of therapy. A high index of suspicion should be maintained in patients with chronic health problems presenting with signs and symptoms of upper gastrointestinal bleeding because AEN can carry an unfavorable prognosis in these patients.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.