Evidence map›Paper›PMID 35711791›Full record

ArticleFrontiers in veterinary science2022

Electrical Impedance Myography in Dogs With Degenerative Myelopathy.

Joseph B Kowal, Sarah A Verga, Sarbesh R Pandeya, Randall J Cochran, Julianna C Sabol, Seward B Rutkove, Joan R Coates

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06491732 (Electrical Impedance Myography Via the Myolex mScan as an ALS Biomarker), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06491732 recruitingnot on this mapstarted 2025, after this paper: background citation

Electrical Impedance Myography Via the Myolex mScan as an ALS Biomarker

TypeobservationalSponsorBeth Israel Deaconess Medical CenterRan2025 to 2027Enrolled80ConditionsAmyotrophic Lateral SclerosisArmsElectrical Impedance Myography
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Common Neurologic Diseases in Geriatric Dogs.Animals : an open access journal from MDPI · 2024
    Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Joseph B KowalDepartment of Veterinary Medicine and Surgery, University of Missouri, College of Veterinary Medicine, Columbia, MO, United States.
Sarah A VergaDepartment of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Sarbesh R PandeyaDepartment of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Randall J CochranDepartment of Veterinary Medicine and Surgery, University of Missouri, College of Veterinary Medicine, Columbia, MO, United States.
Julianna C SabolDepartment of Veterinary Medicine and Surgery, University of Missouri, College of Veterinary Medicine, Columbia, MO, United States.
Seward B RutkoveDepartment of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Joan R CoatesDepartment of Veterinary Medicine and Surgery, University of Missouri, College of Veterinary Medicine, Columbia, MO, United States.
Missouri College · USBeth Israel Deaconess Medical Center · USHarvard University · USUniversity of Missouri · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canine degenerative myelopathy (DM) leads to disuse and neurogenic muscle atrophy. Currently there is a lack of non-invasive quantitative measures of muscle health in dogs with DM. Muscle pathology has been previously quantified in other disorders using the technique of electrical impedance myography (EIM) but it has not been reported for DM. The objective of this study was to compare EIM between DM-affected and similar aged healthy dogs as well as assess EIM changes over time in DM-affected dogs. Multifrequency EIM was performed on DM affected dogs at baseline and during disease progression and on age-matched healthy dogs. Muscles evaluated in the pelvic limbs included the craniotibialis, gastrocnemius, gracilis, sartorius, and biceps femoris. The 100 kHz phase angle was extracted from the full frequency set for analysis. Phase values were lower in DM dogs as compared to healthy controls. Specifically, phase of the gastrocnemius was lower on the left (θ = 7.69, 13.06;

Indexed as

atrophycanine (dog)degenerative myelopathyelectrical impedance myography (EIM)neuromuscularSOD1

Identifiers

PMID35711791
PMCPMC9196121
OpenAlexW4281996230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.