Evidence map›Paper›PMID 35711667›Full record

ArticleFrontiers in cellular and infection microbiology2022

A Malaria Parasite Cross Reveals Genetic Determinants of

Sudhir Kumar, Xue Li, Marina McDew-White, Ann Reyes, Elizabeth Delgado, Abeer Sayeed, Meseret T Haile, Biley A Abatiyow, Spencer Y Kennedy, Nelly Camargo and 10 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  7. AmBio · 2024
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  11. Cultivation of Asexual Intraerythrocytic Stages ofPathogens (Basel, Switzerland) · 2023
    Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 3 countries.

Sudhir KumarCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States.
Xue LiProgram in Disease Intervention and Prevention, Texas Biomedical Research Institute, San Antonio, TX, United States.
Marina McDew-WhiteProgram in Disease Intervention and Prevention, Texas Biomedical Research Institute, San Antonio, TX, United States.
Ann ReyesProgram in Disease Intervention and Prevention, Texas Biomedical Research Institute, San Antonio, TX, United States.
Elizabeth DelgadoProgram in Disease Intervention and Prevention, Texas Biomedical Research Institute, San Antonio, TX, United States.
Abeer SayeedProgram in Disease Intervention and Prevention, Texas Biomedical Research Institute, San Antonio, TX, United States.
Meseret T HaileCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States.
Biley A AbatiyowCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States.
Spencer Y KennedyCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States.
Nelly CamargoCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States.
Lisa A CheckleyDepartment of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN, United States.
Katelyn V BrennemanDepartment of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN, United States.
Katrina A Button-SimonsDepartment of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN, United States.
Manoj T DuraisinghImmunology and Infectious Diseases Department, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
Ian H CheesemanProgram in Host Pathogen Interactions, Texas Biomedical Research Institute, San Antonio, TX, United States.
Stefan H I KappeCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States.
François NostenShoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.
Michael T FerdigDepartment of Biological Sciences, Eck Institute for Global Health, University of Notre Dame, Notre Dame, IN, United States.
Ashley M VaughanCenter for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States.
Tim J C AndersonProgram in Disease Intervention and Prevention, Texas Biomedical Research Institute, San Antonio, TX, United States.
Texas Biomedical Research Institute · USInfectious Disease Research Institute · USUniversity of Notre Dame · USHarvard University · USShoklo Malaria Research Unit · THUniversity of Washington · US

Funding

Systems genetics of artemisinin resistanceP01AI127338 · NIAID · UNIVERSITY OF NOTRE DAME · PI Michael T Ferdig, Ashley M Vaughan · 2017 to 2026
$21.3M
Mapping Drug Resistance Genes in Plasmodium falciparumR37AI048071 · NIAID · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI ANDERSON, TIM J · 2012 to 2021
$7.9M
A systems genetics approach to determine factors regulating Plasmodium falciparum sporozoite infectivityR21AI133369 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI VAUGHAN, ASHLEY M · 2017 to 2018
$525k
NIAID NIH HHS P01 AI127338NIAID NIH HHS R21 AI133369NIAID NIH HHS R37 AI048071Wellcome Trust
6 · The paper itself

Abstract

What genes determine

Indexed as

Malaria, FalciparumPlasmodium falciparumAnimalsCrosses, GeneticCulture MediaGene FrequencyMiceQuantitative Trait LociCulture MediaAlbuMAXbulk segregant analysisgenetic crossPlasmodium falciparumserum

Identifiers

PMID35711667
PMCPMC9197316
OpenAlexW4281700664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.