Evidence map›Paper›PMID 35711662›Full record

ArticleFrontiers in cellular and infection microbiology2022

Spaceflight Analogue Culture Enhances the Host-Pathogen Interaction Between

Jennifer Barrila, Jiseon Yang, Karla P Franco Meléndez, Shanshan Yang, Kristina Buss, Trenton J Davis, Bruce J Aronow, Heather D Bean, Richard R Davis, Rebecca J Forsyth and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

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  9. TET3-mediated DNA oxidation is essential for intestinal epithelial cell response to stressors.Proceedings of the National Academy of Sciences of the United States of America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 1 country.

Jennifer BarrilaBiodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, United States.
Jiseon YangBiodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, United States.
Karla P Franco MeléndezBiodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, United States.
Shanshan YangBioinformatics Core Facility, Bioscience, Knowledge Enterprise, Arizona State University, Tempe, AZ, United States.
Kristina BussBioinformatics Core Facility, Bioscience, Knowledge Enterprise, Arizona State University, Tempe, AZ, United States.
Trenton J DavisBiodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, United States.
Bruce J AronowDivision of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.
Heather D BeanBiodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, United States.
Richard R DavisBiodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, United States.
Rebecca J ForsythBiodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, United States.
C Mark OttBiomedical Research and Environmental Sciences Division, NASA Johnson Space Center, Houston, TX, United States.
Sandhya GangarajuBiodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, United States.
Bianca Y KangBiodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, United States.
Brian HanrattyBioinformatics Core Facility, Bioscience, Knowledge Enterprise, Arizona State University, Tempe, AZ, United States.
Seth D NydamDepartment of Animal Care & Technologies, Arizona State University, Tempe, AZ, United States.
Eric A NaumanSchool of Mechanical Engineering, Weldon School of Biomedical Engineering and Department of Basic Medical Sciences, Purdue University, West Lafayette, IN, United States.
Wei KongBiodesign Center for Immunotherapy, Vaccines and Virotherapy, Arizona State University, Tempe, AZ, United States.
Jason SteelBioinformatics Core Facility, Bioscience, Knowledge Enterprise, Arizona State University, Tempe, AZ, United States.
Cheryl A NickersonBiodesign Center for Fundamental and Applied Microbiomics, Arizona State University, Tempe, AZ, United States.
Arizona State University · USAgricultural Research Service · USCincinnati Children's Hospital Medical Center · USJohnson Space Center · USPurdue University West Lafayette · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical forces associated with spaceflight and spaceflight analogue culture regulate a wide range of physiological responses by both bacterial and mammalian cells that can impact infection. However, our mechanistic understanding of how these environments regulate host-pathogen interactions in humans is poorly understood. Using a spaceflight analogue low fluid shear culture system, we investigated the effect of Low Shear Modeled Microgravity (LSMMG) culture on the colonization of

Indexed as

BiomimeticsSpace FlightAnimalsCoculture TechniquesHost-Pathogen InteractionsHumansMammalsSalmonella typhimuriumcolonfluid sheargene expressionHfqmechanobiologyRotating Wall VesselspaceflightTyphimurium

Identifiers

PMID35711662
PMCPMC9195300
OpenAlexW4281705783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.