Evidence map›Paper›PMID 35711615›Full record

ArticleJournal of market access & health policy2022

Public health impact of COVID-19 in French ambulatory patients with at least one risk factor for severe disease.

Aurélie Millier, Romain Supiot, Kelly Benyounes, Valérie Machuron, Katell Le Lay, Marine Sivignon, Claire Leboucher, Cécile Blein, François Raffi

Open access · goldAbstract read
In one paragraph

Article in Journal of market access & health policy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Aurélie MillierHEOR/HTA, Creativ-Ceutical, Paris, France.
Romain SupiotHEOR/HTA, Creativ-Ceutical, Paris, France.ORCID https://orcid.org/0000-0002-8416-3063
Kelly BenyounesHEOR, Roche SA France, Paris, France.
Valérie MachuronHEOR, Roche SA France, Paris, France.
Katell Le LayHEOR, Roche SA France, Paris, France.
Marine SivignonHEOR/HTA, Creativ-Ceutical, Paris, France.
Claire LeboucherHEOR/HTA, Creativ-Ceutical, Paris, France.
Cécile BleinHEOR/HTA, Creativ-Ceutical, Paris, France.
François RaffiService de Maladies Infectieuses et Tropicales, CHU de Nantes, Nantes, France.
Creativ-Ceutical (France) · FRRoche (France) · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Quantification of COVID-19 burden may be useful to support the future allocation of resources. Objective: To evaluate the public health impact of COVID-19 in French ambulatory patients with at least one risk factor for severe disease. Study design: A Markov model was used to estimate life years, costs, number of hospitalisations, number of deaths and long/prolonged COVID forms over a time horizon of 2 years. The hospitalisation probabilities were derived from an early access cohort, and the hospitalisation stay characteristics were derived from the French national hospital discharge database. Several scenario analyses were conducted. Results: The number of hospitalisations reached 256 per 1,000 patients over the acute phase (first month of simulation), and 382 per 1,000 patients over 2 years. The number of deaths was 37 per 1,000 patients, and the number of long/prolonged COVID forms reached 407 per 1,000 patients. These translated into a reduction of 0.7 days of life per patient in the first month, with an associated cost of €1,578, and a reduction of 27 days of life over the time horizon, with an associated cost of €4,280. The highest burden was observed for patients over 80 years old, and those not vaccinated. The scenarios with a less severe situation or new treatments available showed a non-negligible burden reduction. Conclusion: This study allowed us to quantify the considerable burden related to COVID-19 in infected patients, with at least one risk factor for severe form. Strategies with the ability to substantially reduce this burden in France are urgently required.

Indexed as

COVID-19modelpublic health impactsimulation

Identifiers

PMID35711615
PMCPMC9196736
OpenAlexW4281737819

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.