Evidence map›Paper›PMID 35711589›Full record

ArticleFrontiers in psychiatry2022

Prevalence of Anti-neural Autoantibodies in a Psychiatric Patient Cohort-Paradigmatic Application of Criteria for Autoimmune-Based Psychiatric Syndromes.

Niels Hansen, Aaron Levin Juhl, Insa Maria Grenzer, Kristin Rentzsch, Jens Wiltfang, Dirk Fitzner

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Niels HansenDepartment of Psychiatry and Psychotherapy, University of Göttingen, Göttingen, Germany.
Aaron Levin JuhlDepartment of Psychiatry and Psychotherapy, University of Göttingen, Göttingen, Germany.
Insa Maria GrenzerDepartment of Psychiatry and Psychotherapy, University of Göttingen, Göttingen, Germany.
Kristin RentzschEuroimmun Reference Laboratory, Lübeck, Germany.
Jens WiltfangDepartment of Psychiatry and Psychotherapy, University of Göttingen, Göttingen, Germany.
Dirk FitznerDepartment of Neurology, University Medical Center Göttingen, Göttingen, Germany.
University of Göttingen · DEEuroimmun Medizinische Labordiagnostika (Germany) · DEGerman Center for Neurodegenerative Diseases · DEUniversitätsmedizin Göttingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Anti-neural autoantibodies associated with psychiatric syndromes is an increasing phenomenon in psychiatry. Our investigation aimed to assess the frequency and type of neural autoantibodies associated with distinct psychiatric syndromes in a mixed cohort of psychiatric patients. Methods: We recruited 167 patients retrospectively from the Department of Psychiatry and Psychotherapy, University Medical Center Göttingen for this study. Clinical features including the assessment of psychopathology Results: We divided patients in three different groups: (1) psychiatric patients with CSF and/or serum autoantibodies [PSYCH-AB+, Conclusions: Neural autoantibodies were detected mainly in patients presenting neurocognitive and mood disorders in our psychiatric cohort. The phenotypical appearance of psychiatric syndromes in conjunction with neural autoantibodies did not differ from those without neural autoantibodies. More research is therefore warranted to optimize biomarker research to help clinicians differentiate patients with potential neural autoantibodies when a rapid clinical response is required as in delirium states.

Indexed as

blooddeliriumdementianeuronal autoantibodiespsychiatry

Identifiers

PMID35711589
PMCPMC9196031
OpenAlexW4281698755

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.