ArticleFrontiers in nutrition2022
The Correlation of Total Percent Fat With Alterations in Cholesterol and Triglycerides in Adults.
Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Alternative organelle targeting of OPA1 mediates fatty acid release from lipid droplets.bioRxiv : the preprint server for biology · 2026Article
- Pinocembrin ameliorates non-alcoholic fatty liver disease by activating Nrf2/HO-1 and inhibiting the NF-κB signaling pathway.Histology and histopathology · 2025Article
- Relation of skinfold thickness with the serum lipids, glucose and blood pressure among Indian sedentary office workers.Journal of health, population, and nutrition · 2024Article
- The Association Between Blood Mercury and Lipid Biomarkers in US Hypertensive Adults.Biological trace element research · 2024Article
- The different association between fat mass distribution and intake of three major nutrients in pre- and postmenopausal women.PloS one · 2024Article
- Article
- Reduced cardiovascular reserve capacity in long-term allogeneic stem cell transplant survivors.Scientific reports · 2023Article
- Post-treatment serum triglyceride: An effective biomarker for body fat mass and overall survival in esophageal squamous cell cancer patients treated with chemoradiotherapy.Frontiers in nutrition · 2022Article
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Authors and funding
5 authors.
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Abstract
Background: To evaluate the detailed relationship between total percent fat (TPF) and cardiovascular disease (CVD)-related lipid biomarkers among adults and find a non-invasive indicator for screening and monitoring of the high CVD risk population. Methods: Data of 13,160 adults were obtained from the National Health and Examination Survey (NHANES) from 1999 to 2018. TPF was assessed by dual-energy x-ray absorptiometry (DXA), and CVD-related lipid biomarkers included total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C). Multivariable linear regression models were used to examine associations between TPF with four kinds of lipid biomarkers, and smooth curve fittings and generalized additive models were used to address the non-linear relationship between them. The inflection points were calculated by the recursive algorithm when non-linearities were detected and then weighted two-piecewise linear regression models were constructed. Results: In multivariable regression, increasing TPF was positively associated with TC, TG, and LDL-C and negatively with HDL-C (all Conclusions: Total percent fat was significantly associated with CVD-related lipid biomarkers in adults, positively with TC, TG, and LDL-C and negatively with HDL-C. It could be used as a non-invasive screener and monitor of high CVD risk population when their TPF values were less than the inflection points.
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