Evidence map›Paper›PMID 35711531›Full record

SynthesisContrast media & molecular imaging2022

Correlation Analysis of DNA Methylation in the von Willebrand Factor Promoter Region and the Risk of Unexplained Recurrent Hemophilia: Systematic Review and Meta-Analysis.

Jing Dong, Jie Li, Ling Yang, Qiuhong Kong, Zhirong Zhang, Hong Zhang

RetractedOpen access · hybridAbstract readMeta-AnalysisSystematic ReviewRetracted Publication
In one paragraph

Synthesis in Contrast media & molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jing DongThe Second Affiliated Hospital of Shandong First Medical University, No. 366 Taishan Street, Tai'an, Shandong 271000, China.ORCID 0000-0001-8941-1356
Jie LiThe Second Affiliated Hospital of Shandong First Medical University, No. 366 Taishan Street, Tai'an, Shandong 271000, China.
Ling YangThe Second Affiliated Hospital of Shandong First Medical University, No. 366 Taishan Street, Tai'an, Shandong 271000, China.
Qiuhong KongThe Second Affiliated Hospital of Shandong First Medical University, No. 366 Taishan Street, Tai'an, Shandong 271000, China.
Zhirong ZhangThe Second Affiliated Hospital of Shandong First Medical University, No. 366 Taishan Street, Tai'an, Shandong 271000, China.
Hong ZhangThe Second Affiliated Hospital of Shandong First Medical University, No. 366 Taishan Street, Tai'an, Shandong 271000, China.
Affiliated Hospital of Taishan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study systematically reviewed the effect of DNA methylation in the promoter region of the coagulation factor vWF gene on the risk of unexplained recurrent hemophilia. PubMed, Medline, Web of Science, and other computers were used to search the database, and the statistical randomized controlled trials of coagulation factor vWF in the risk analysis of unknown recurrent hemophilia were collected. The Cochrane systematic evaluation method was used to evaluate the quality of the included kinds of literature, and Revman5 software was used to sort out and analyze the kinds of literature. Meta-analysis showed that there was a statistical difference between the experimental group and the control group in case fatality rate (OR = 1.76, 95% CI (1.29, 2.39),

Indexed as

Hemophilia ADNA MethylationHumansPromoter Regions, Geneticvon Willebrand Factorvon Willebrand Factor

Identifiers

PMID35711531
PMCPMC9187466
OpenAlexW4281710580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.