Evidence map›Paper›PMID 35711455›Full record

ArticleFrontiers in immunology2022

Tumor-Derived Exosomes Regulate Apoptosis of CD45

Shixiang Lu, Zhen Sun, Lili Liu, Peng Li, Bin Li, Wenjing Li, Zhaojun Wu, Mingming Zhao, Wenna Liu, Yongjie Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Divergent CD45Frontiers in immunology · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Application of exosomes in tumor immunity: recent progresses.Frontiers in cell and developmental biology · 2024
    Review
  8. Circulating CD45Frontiers in medical technology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Shixiang LuDepartment of Special Medicine, School of Basic Medicine, Qingdao University, Qingdao, China.
Zhen SunDepartment of Research and Development, Sino-Cell Biomed Co., Ltd., Qingdao, China.
Lili LiuSchool of Basic Medicine, Qingdao University, Qingdao, China.
Peng LiDepartment of Thoracic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Bin LiDepartment of Research and Development, Sino-Cell Biomed Co., Ltd., Qingdao, China.
Wenjing LiDepartment of Research and Development, Sino-Cell Biomed Co., Ltd., Qingdao, China.
Zhaojun WuDepartment of Research and Development, Sino-Cell Biomed Co., Ltd., Qingdao, China.
Mingming ZhaoDepartment of Research and Development, Sino-Cell Biomed Co., Ltd., Qingdao, China.
Wenna LiuDepartment of Research and Development, Sino-Cell Biomed Co., Ltd., Qingdao, China.
Yongjie WangDepartment of Thoracic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Bin WangDepartment of Special Medicine, School of Basic Medicine, Qingdao University, Qingdao, China.
Sino Biological (China) · CNQingdao University · CNAffiliated Hospital of Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer has the highest mortality rate among human cancers, and the majority of deaths result from metastatic spread. The tumor microenvironment plays an important role in suppressing the immune surveillance and elimination of tumor cells. A few studies have reported the presence of CD45

Indexed as

ExosomesLung NeoplasmsApoptosisEpithelial Cell Adhesion MoleculeHumansLeukocytes, MononuclearTumor MicroenvironmentEPCAM protein, humanEpithelial Cell Adhesion MoleculeapoptosisCD45+EpCAM+ cellsHCC827 cellsPBMCtumor-derived exosomes

Identifiers

PMID35711455
PMCPMC9192438
OpenAlexW4281699628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.