Evidence map›Paper›PMID 35711408›Full record

ArticleFrontiers in immunology2022

Characterization of Zymosan-Modulated Neutrophils With Neuroregenerative Properties.

Andrew D Jerome, Jeffrey R Atkinson, Arnetta L McVey Moffatt, Jesse A Sepeda, Benjamin M Segal, Andrew R Sas

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andrew D JeromeDepartment of Neurology, Ohio State Medical Center, Columbus, OH, United States.
Jeffrey R AtkinsonDepartment of Neurology, Ohio State Medical Center, Columbus, OH, United States.
Arnetta L McVey MoffattDepartment of Neurology, Ohio State Medical Center, Columbus, OH, United States.
Jesse A SepedaDepartment of Neurology, Ohio State Medical Center, Columbus, OH, United States.
Benjamin M SegalDepartment of Neurology, Ohio State Medical Center, Columbus, OH, United States.
Andrew R SasDepartment of Neurology, Ohio State Medical Center, Columbus, OH, United States.
The Ohio State University · US

Funding

Immune mediated regeneration of retinal ganglion cell axons following optic nerve traumaR01EY028350 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEGAL, BENJAMIN M · 2017 to 2020
$1.5M
A novel inflammatory cell with neuroprotective and neuroregenerative propertiesR01EY029159 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SEGAL, BENJAMIN M · 2018 to 2022
$1.4M
Neutrophil driven recovery from traumatic and ischemic optic neuropathyK08EY029362 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SAS, ANDREW ROBERT · 2018 to 2022
$898k
Defining the Role of Interferon Alpha in HIV EncephalitisF31NS054592 · NINDS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI SAS, ANDREW R · 2007 to 2007
$31k
NEI NIH HHS K08 EY029362NEI NIH HHS R01 EY028350NEI NIH HHS R01 EY029159NINDS NIH HHS F31 NS054592
6 · The paper itself

Abstract

Recent studies using advanced techniques such as single cell RNA sequencing (scRNAseq), high parameter flow cytometry, and proteomics reveal that neutrophils are more heterogeneous than previously appreciated. Unique subsets have been identified in the context of bacterial and parasitic infections, cancer, and tissue injury and repair. The characteristics of infiltrating neutrophils differ depending on the nature of the inflammation-inciting stimulus, the stage of the inflammatory response, as well as the tissue microenvironment in which they accumulate. We previously described a new subpopulation of immature Ly6G

Indexed as

AxonsNeutrophilsAnimalsInflammationMiceNerve RegenerationZymosanZymosanheterogeneityneutrophilsproteomicsregenerationtranscriptomics

Identifiers

PMID35711408
PMCPMC9195616
OpenAlexW4281745375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.