Evidence map›Paper›PMID 35711312›Full record

ArticleFrontiers in physiology2022

Vitamin D Receptor-Dependent Protective Effect of Moderate Hypoxia in a Mouse Colitis Model.

Zheng Wang, Hong Yang, Hong Lv, Changzhi Huang, Jiaming Qian

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Gut distress and interventionFrontiers in public health · 2023
    Pooled it
  2. Review
  3. Vitamin DEuropean journal of nutrition · 2024
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Zheng WangDepartment of Gastroenterology, PUMC Hospital, CAMS and PUMC, Beijing, China.
Hong YangDepartment of Gastroenterology, PUMC Hospital, CAMS and PUMC, Beijing, China.
Hong LvDepartment of Gastroenterology, PUMC Hospital, CAMS and PUMC, Beijing, China.
Changzhi HuangState Key Laboratory of Molecular Oncology, Cancer Hospital, CAMS and PUMC, Beijing, China.
Jiaming QianDepartment of Gastroenterology, PUMC Hospital, CAMS and PUMC, Beijing, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNPeking Union Medical College Hospital · CNState Key Laboratory of Molecular Oncology

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although hypoxia is important for maintaining the intestinal barrier, its effect on the barrier during acute colitis and the underlying mechanisms are not fully understood. To explore the influence of hypoxia in dextran sulfate sodium (DSS)-induced colitis mice and the role of hypoxia-inducible factor (HIF) and vitamin D receptor (VDR) in the process. Colitis mice were subjected to hypoxia to detect intestinal barrier function changes. And the mechanisms were explored

Indexed as

DSS-induced colitisHIF-1α (hypoxia inducible factor-1α)hypoxiaintestinal barrierVitamin D receptor (VDR)

Identifiers

PMID35711312
PMCPMC9195869
OpenAlexW4281614282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.