Evidence map›Paper›PMID 35711149›Full record

ArticleThe Journal of international medical research2022

Leiming Sun, Jing Sun, Shibiao Ding

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Leiming SunDepartment of Critical Care Medicine, Hangzhou Red Cross Hospital, Hangzhou, Zhejiang Province, PR China.ORCID https://orcid.org/0000-0002-1663-1785
Jing SunDepartment of Critical Care Medicine, Hangzhou Red Cross Hospital, Hangzhou, Zhejiang Province, PR China.
Shibiao DingClinical Medical Laboratory Center, Hangzhou Red Cross Hospital, Hangzhou, Zhejiang Province, PR China.
Hangzhou Red Cross Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMultidrug-resistant

methodsMDR KP strains isolated from clinical samples were assessed for antibiotic susceptibility using the broth microdilution method. Twenty consecutive MDR KP clinical isolates from patients with bloodstream infections were examined in this study. The experiments were conducted at the Bacterial Laboratory of Tongde Hospital from March to August 2021. Antibiotic combination tests were performed using the minimum inhibitory concentration (MIC) test, and the sum of the fractional inhibitory concentration was used to assess synergy.

resultsFollowing treatment with a combination of two antibiotic agents, the MIC50 and MIC90 values decreased compared with that before treatment. MIC50 decreased by at least 50%, with one value reduced to 6.25% of the pretreatment value. None of the antibiotic combinations were antagonistic. Combination of polymyxin B with rifampicin or tigecycline had a synergistic effect on 70% and 65% of the strains, respectively.

conclusions

Indexed as

Klebsiella InfectionsSepsisAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialHumansKlebsiella pneumoniaeMicrobial Sensitivity TestsPolymyxin BRifampinTigecyclineAnti-Bacterial AgentsPolymyxin BRifampinTigecyclineimipenemMultidrug-resistant Klebsiella pneumoniaeold antibiotic combinationspolymyxin Brifampicinsynergistic effecttigecycline

Identifiers

PMID35711149
PMCPMC9210083
OpenAlexW4283011361

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.