Evidence map›Paper›PMID 35710919›Full record

ArticleScientific reports2022

Serum folate levels and hypertension.

Yoonkyung Lee, Sangshin Park

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yoonkyung LeeGraduate School of Urban Public Health, University of Seoul, 163 Seoulsiripdae-ro, Dongdaemun-gu, Seoul, 02504, Republic of Korea.
Sangshin ParkGraduate School of Urban Public Health, University of Seoul, 163 Seoulsiripdae-ro, Dongdaemun-gu, Seoul, 02504, Republic of Korea. dvm.spark@gmail.com.
University of Seoul · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to examine the association between serum folate levels and hypertension in Korean adults. Our study population was 6343 Korean adults whose blood pressure and folate levels were measured in the Korea National Health and Nutrition Examination Survey 2016-2018. We aggregated the study populations into quintiles according to serum folate levels (1.5-4.3, 4.4-5.7, 5.8-7.5, 7.6-10.3, and 10.4-35.9 ng/mL). Multivariable logistic and linear regression models were used to analyze the relationships between serum folate levels, blood pressure, and hypertension. The weighted average of serum folate levels was 7.4 ng/mL, and the weighted prevalence of hypertension was 30.4% in the study populations. After adjusting for all potential confounders, compared to those in the lowest quintile of serum folate levels, systolic and diastolic blood pressure of the people in the other quintiles were not significantly different. The linear relationship between serum folate levels and blood pressure was not statistically significant. The odds for hypertension were not significantly different across the quintiles of serum folate levels. This study showed high serum folate levels was not significantly associated with lowering hypertension in Korean adults.

Indexed as

HypertensionAdultBlood PressureCross-Sectional StudiesFolic AcidHumansNutrition SurveysRepublic of KoreaRisk FactorsFolic Acid

Identifiers

PMID35710919
PMCPMC9203455
OpenAlexW4282984530

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.