Evidence map›Paper›PMID 35710904›Full record

ReviewNature communications2022

A sound approach to advancing healthcare systems: the future of biomedical acoustics.

Joseph Rufo, Peiran Zhang, Ruoyu Zhong, Luke P Lee, Tony Jun Huang

Abstract readReview
In one paragraph

Review in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. External Stimuli-Activable Single-Atom Nanozymes for Bioapplications.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  7. Acoustofluidic Biosensors.Micromachines · 2026
    Review
  8. Article
  9. Article
  10. Parabiosis, Assembloids, Organoids (PAO).Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  11. Article
  12. Article
  13. Review
  14. Enhancing cancer therapyLab on a chip · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joseph RufoDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA.ORCID http://orcid.org/0000-0001-7408-2393
Peiran ZhangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA.
Ruoyu ZhongDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA.
Luke P LeeRenal Division and Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA. lplee@bwh.harvard.edu.ORCID http://orcid.org/0000-0002-1436-4054
Tony Jun HuangDepartment of Mechanical Engineering and Materials Science, Duke University, Durham, NC, 27708, USA. tony.huang@duke.edu.ORCID http://orcid.org/0000-0003-1205-3313

Funding

Acoustofluidic Separation of Placental Nanovesicle Subpopulations in Obstetrical DiseasesR01HD103727 · NICHD · STANFORD UNIVERSITY · PI HUANG, TONY JUN, SADOVSKY, YOEL · 2021 to 2025
$2.6M
Development of a digital acoustofluidic system for automating liquid handling in biomedical researchR01GM141055 · NIGMS · DUKE UNIVERSITY · PI HUANG, TONY JUN · 2021 to 2024
$1.9M
AFS/SERS Saliva-based SARS-CoV-2 Earliest Infection and Antibodies DetectionU18TR003778 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HUANG, TONY JUN, KIM, YONG · 2021 to 2022
$1.8M
Integrated Acoustofluidic Plasmonic Molecular Diagnostic System for Detecting MicroRNA BiomarkersR01GM135486 · NIGMS · DUKE UNIVERSITY · PI VO-DINH, TUAN · 2020 to 2023
$1.8M
Acoustofluidic Separation (AFS), Purification and Raman Spectral Fingerprinting of Single EVs: From Cell of Origin to Target Cell and BiofluidsUH3TR002978 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GALL, KENNETH A, HUANG, TONY JUN · 2021 to 2022
$1.8M
Enabling Efficient, Fast, Biocompatible Exosome Separation via AcoustofluidicsR01GM132603 · NIGMS · DUKE UNIVERSITY · PI HUANG, TONY JUN · 2019 to 2022
$1.7M
NCATS NIH HHS U18 TR003778NCATS NIH HHS UH3 TR002978NICHD NIH HHS R01 HD103727NIGMS NIH HHS R01 GM132603NIGMS NIH HHS R01 GM135486NIGMS NIH HHS R01 GM141055
6 · The paper itself

Abstract

Newly developed acoustic technologies are playing a transformational role in life science and biomedical applications ranging from the activation and inactivation of mechanosensitive ion channels for fundamental physiological processes to the development of contact-free, precise biofabrication protocols for tissue engineering and large-scale manufacturing of organoids. Here, we provide our perspective on the development of future acoustic technologies and their promise in addressing critical challenges in biomedicine.

Indexed as

AcousticsSoundDelivery of Health CareOrganoidsTissue Engineering

Identifiers

PMID35710904
PMCPMC9200942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.