Evidence map›Paper›PMID 35710792›Full record

ArticleScientific data2022

A harmonized chemical monitoring database for support of exposure assessments.

Kristin K Isaacs, Jonathan T Wall, Ashley R Williams, Kevin A Hobbie, Jon R Sobus, Elin Ulrich, David Lyons, Kathie L Dionisio, Antony J Williams, Christopher Grulke and 3 more

Abstract read
In one paragraph

Article in Scientific data, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Identifying differences in U.S. exposure to ubiquitous carcinogens.International journal of hygiene and environmental health · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. The chemical landscape of high-throughput new approach methodologies for exposure.Journal of exposure science & environmental epidemiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kristin K IsaacsU.S. Environmental Protection Agency, Center for Computational Toxicology and Exposure, 109 T.W. Alexander Drive, Research Triangle Park, NC, 27709, USA. Isaacs.kristin@epa.gov.ORCID 0000-0001-9547-1654
Jonathan T WallU.S. Environmental Protection Agency, Center for Computational Toxicology and Exposure, 109 T.W. Alexander Drive, Research Triangle Park, NC, 27709, USA.ORCID 0000-0002-4610-8645
Ashley R WilliamsICF International, 2635 Meridian Pkwy #200, Durham, NC, 27713, USA.
Kevin A HobbieICF International, 2635 Meridian Pkwy #200, Durham, NC, 27713, USA.ORCID 0000-0003-4645-0923
Jon R SobusU.S. Environmental Protection Agency, Center for Computational Toxicology and Exposure, 109 T.W. Alexander Drive, Research Triangle Park, NC, 27709, USA.
Elin UlrichU.S. Environmental Protection Agency, Center for Computational Toxicology and Exposure, 109 T.W. Alexander Drive, Research Triangle Park, NC, 27709, USA.
David LyonsU.S. Environmental Protection Agency, Center for Computational Toxicology and Exposure, 109 T.W. Alexander Drive, Research Triangle Park, NC, 27709, USA.
Kathie L DionisioU.S. Environmental Protection Agency, Center for Computational Toxicology and Exposure, 109 T.W. Alexander Drive, Research Triangle Park, NC, 27709, USA.
Antony J WilliamsU.S. Environmental Protection Agency, Center for Computational Toxicology and Exposure, 109 T.W. Alexander Drive, Research Triangle Park, NC, 27709, USA.ORCID 0000-0002-2668-4821
Christopher GrulkeU.S. Environmental Protection Agency, Center for Computational Toxicology and Exposure, 109 T.W. Alexander Drive, Research Triangle Park, NC, 27709, USA.ORCID 0000-0001-5606-7560
Caroline A FosterICF International, 2635 Meridian Pkwy #200, Durham, NC, 27713, USA.
Josiah McCoyICF International, 2635 Meridian Pkwy #200, Durham, NC, 27713, USA.
Charles BevingtonU.S. Consumer Product Safety Commission 5 Research Place Rockville, Rockville, MD, 20850, USA.ORCID 0000-0003-0932-969X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Direct monitoring of chemical concentrations in different environmental and biological media is critical to understanding the mechanisms by which human and ecological receptors are exposed to exogenous chemicals. Monitoring data provides evidence of chemical occurrence in different media and can be used to inform exposure assessments. Monitoring data provide required information for parameterization and evaluation of predictive models based on chemical uses, fate and transport, and release or emission processes. Finally, these data are useful in supporting regulatory chemical assessment and decision-making. There are a wide variety of public monitoring data available from existing government programs, historical efforts, public data repositories, and peer-reviewed literature databases. However, these data are difficult to access and analyze in a coordinated manner. Here, data from 20 individual public monitoring data sources were extracted, curated for chemical and medium, and harmonized into a sustainable machine-readable data format for support of exposure assessments.

Identifiers

PMID35710792
PMCPMC9203490

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.