Evidence map›Paper›PMID 35710689›Full record

ArticleScientific reports2022

Evaluating anticipatory control strategies for their capability to cope with step-down perturbations in computer simulations of human walking.

Lucas Schreff, Daniel F B Haeufle, Johanna Vielemeyer, Roy Müller

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lucas SchreffDepartment of Neurology/Department of Orthopedic Surgery, Klinikum Bayreuth GmbH, Bayreuth, Germany. lucas.schreff@gmx.de.
Daniel F B HaeufleHertie Institute for Clinical Brain Research and Center for Integrative Neuroscience, Tübingen, Germany.
Johanna VielemeyerDepartment of Neurology/Department of Orthopedic Surgery, Klinikum Bayreuth GmbH, Bayreuth, Germany.
Roy MüllerDepartment of Neurology/Department of Orthopedic Surgery, Klinikum Bayreuth GmbH, Bayreuth, Germany.
Bayreuth Medical Center · DEHertie Institute for Clinical Brain Research · DEUniversity of Bayreuth · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous simulation studies investigated the role of reflexes and central pattern generators to explain the kinematic and dynamic adaptations in reaction to step-down perturbations. However, experiments also show preparatory adaptations in humans based on visual anticipation of a perturbation. In this study, we propose a high-level anticipatory strategy augmenting a low-level muscle-reflex control. This strategy directly changes the gain of the reflex control exclusively during the last contact prior to a drop in ground level. Our simulations show that especially the anticipatory reduction of soleus activity and the increase of hamstrings activity result in higher robustness. The best results were obtained when the change in stimulation of the soleus muscle occurred 300 ms after the heel strike of the contralateral leg. This enabled the model to descend perturbation heights up to - 0.21 m and the resulting kinematic and dynamic adaptations are similar to the experimental observations. This proves that the anticipatory strategy observed in experiments has the purpose of increasing robustness. Furthermore, this strategy outperforms other reactive strategies, e.g., pure feedback control or combined feedback and feed-forward control, with maximum perturbation heights of - 0.03 and - 0.07 m, respectively.

Indexed as

GaitWalkingBiomechanical PhenomenaComputer SimulationElectromyographyHumansMuscle, Skeletal

Identifiers

PMID35710689
PMCPMC9203805
OpenAlexW4283009887

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.