ArticleParasites & vectors2022
Susceptibility of Aedes albopictus and Culex quinquefasciatus to Japanese encephalitis virus.
Article in Parasites & vectors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Mosquito vector competence for Japanese encephalitis virus: a systematic review and meta-analysis update.Parasites & vectors · 2025Pooled it
- From invasion to infection: The worldwide expansion and arboviral transmission potential of Aedes albopictus.The Indian journal of medical research · 2026Review
- Identification and mapping of potential and highly likely vectors for selected vector-borne diseases in the EU and neighbouring countries.EFSA journal. European Food Safety Authority · 2026Article
- Evaluation of vector competence of Culex tritaeniorhynchus and Culex pipiens pallens for Japanese encephalitis virus genotype III and V.Parasites & vectors · 2025Article
- Mosquito populations originating from nonendemic areas have the potential to transmit recently emerging Japanese encephalitis virus genotype IV.Emerging microbes & infections · 2025Article
- Genotype-Specific Vector Competence ofViruses · 2025Article
- Evidence of Transmission Capability in UKViruses · 2025Article
- Sheep serve as amplifying hosts of Japanese encephalitis virus, increasing the risk of human infection.Science advances · 2025Article
- Development of Attractive Toxic Sugar Baits (ATSBs) System and Its Effectiveness in Mosquito Control.Insects · 2025Article
- Historical and current perspectives on Japanese encephalitis in Sulawesi, Indonesia.Veterinary world · 2025Review
- Vector competence of EuropeanCurrent research in parasitology & vector-borne diseases · 2025Article
- The making of a dangerous vector: factors shaping the vector competence ofFrontiers in cellular and infection microbiology · 2025Review
- Integrated mosquito control in Matatang village, Northern Zhejiang, China: an effectiveness assessment.Frontiers in public health · 2025Article
- Host Factor Rab4b PromotesMicroorganisms · 2024Article
- Informing an investment case for Japanese encephalitis vaccine introduction in Bangladesh.Science advances · 2024Article
- Study on the temporal and spatial distribution of Culex mosquitoes in Hanoi, Vietnam.Scientific reports · 2024Article
- Vector competence of Swedish Culex pipiens mosquitoes for Japanese encephalitis virus.Parasites & vectors · 2024Article
- Elucidating the role of dsRNA sensing and Toll6 in antiviral responses ofFrontiers in cellular and infection microbiology · 2023Article
- A case report of Japanese encephalitis in Paracelis, Mountain Province, the Philippines.Western Pacific surveillance and response journal : WPSARArticle
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundJapanese encephalitis virus (JEV) is the principal cause of mosquito-borne encephalitis in human populations within Asia. If introduced into new geographic areas, it could have further implications for public and animal health. However, potential mosquito vectors for virus transmission have not been fully investigated. The Asian tiger mosquito, Aedes albopictus, has emerged in Europe and is now expanding its geographical range into more northerly latitudes. Culex quinquefasciatus, although absent from Europe, has been detected in Turkey, a country with territory in Europe, and could act as a vector for JEV in other regions. To assess the risk of these invasive species acting as vectors for JEV and therefore potentially contributing to its geographical expansion, we have investigated the vector competence of Ae. albopictus and Cx. quinquefasciatus.
methodsTwo colonised lines of Ae. albopictus (Italy and Spain) and a line of Cx. quinquefasciatus (Tanzania) were compared for susceptibility to infection by oral feeding with JEV strain SA-14, genotype III at 10
resultsAedes albopictus from Italy showed no susceptibility to infection with JEV strain SA-14. Conversely, Ae. albopictus colonised in Spain was susceptible and 100% of infected mosquitoes that were subjected to saliva screening expressed viral RNA at 14 dpi. Culex quinquefasciatus was highly susceptible to infection as early as 7 dpi and 50% of infected mosquitoes that were subjected to saliva screening expressed viral RNA at 14 dpi. Infection and dissemination were confirmed in Cx. quinquefasciatus by IHC detection of JEV envelope protein in both the mid-gut and salivary glands.
conclusionsAedes albopictus from two different locations in Europe range from being susceptible to JEV and capable of transmission through to being resistant. Culex quinquefasciatus also appears highly susceptible; therefore, both species could potentially act as vectors for JEV and facilitate the emergence of JEV into new regions.
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