Evidence map›Paper›PMID 35710493›Full record

ReviewJournal of nanobiotechnology2022

Recent development of contrast agents for magnetic resonance and multimodal imaging of glioblastoma.

Danping Zhuang, Huifen Zhang, Genwen Hu, Bing Guo

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Manganese-Templated Nontrivial Structures for MRI and Therapy.Journal of the American Chemical Society · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
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  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Exosome tracking by magnetic resonance imaging.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Danping Zhuang *The Second Clinical Medical College, Jinan University, Shenzhen, Guangdong, 518020, China.
Huifen Zhang *Department of Radiology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, 518020, Guangdong, China.
Genwen HuDepartment of Radiology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, 518020, Guangdong, China. hugenwen@163.com.
Bing GuoSchool of Science and Shenzhen Key Laboratory of Flexible Printed Electronics Technology, Harbin Institute of Technology, Shenzhen, 518055, China. guobing2020@hit.edu.cn.
Southern University of Science and Technology · CNHarbin Institute of Technology · CNJinan University · CN

Funding

Guangdong Basic and Applied Basic Research Foundation 2021A1515110086Start-up Grant at Harbin Institute of Technology (Shenzhen) HA45001108, HA11409049the General Project of Guangdong Natural Science Foundation 2022A1515011781the Science and Technology Innovation Commission of Shenzhen RCBS20200714114910141, JCYJ20210324132816039
6 · The paper itself

Abstract

Glioblastoma (GBM) as the most common primary malignant brain tumor exhibits a high incidence and degree of malignancy as well as poor prognosis. Due to the existence of formidable blood-brain barrier (BBB) and the aggressive growth and infiltrating nature of GBM, timely diagnosis and treatment of GBM is still very challenging. Among different imaging modalities, magnetic resonance imaging (MRI) with merits including high soft tissue resolution, non-invasiveness and non-limited penetration depth has become the preferred tool for GBM diagnosis. Furthermore, multimodal imaging with combination of MRI and other imaging modalities would not only synergistically integrate the pros, but also overcome the certain limitation in each imaging modality, offering more accurate morphological and pathophysiological information of brain tumors. Since contrast agents contribute to amplify imaging signal output for unambiguous pin-pointing of tumors, tremendous efforts have been devoted to advances of contrast agents for MRI and multimodal imaging. Herein, we put special focus on summary of the most recent advances of not only MRI contrast agents including iron oxide-, manganese (Mn)-, gadolinium (Gd)-,

Indexed as

Brain NeoplasmsGlioblastomaContrast MediaHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMultimodal ImagingContrast Mediablood–brain barrierContrast agentsGlioblastomaMRI

Identifiers

PMID35710493
PMCPMC9204881
OpenAlexW4283026464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.