Evidence map›Paper›PMID 35710395›Full record

ArticleBMC sports science, medicine & rehabilitation2022

No effects of a 4-week post-exercise sauna bathing on targeted gut microbiota and intestinal barrier function, and hsCRP in healthy men: a pilot randomized controlled trial.

Joanna Karolkiewicz, David C Nieman, Tomasz Cisoń, Joanna Szurkowska, Mirosława Gałęcka, Dariusz Sitkowski, Zbigniew Szygula

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC sports science, medicine & rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05277597 (Effect of a 4-week Post-exercise Sauna Bathing on Targeted Gut Microbiota and Intestinal Barrier Function in Healthy Men), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05277597 nacompletednot on this map

Effect of a 4-week Post-exercise Sauna Bathing on Targeted Gut Microbiota and Intestinal Barrier Function in Healthy Men: a Randomized Controlled Pilot Trial

TypeinterventionalSponsorPoznan University of Physical EducationRan2020 to 2021Enrolled15ConditionsHealthy MalesArmsThe exercise 60 minutes, 3 times per week, on a bicycle ergometer followed by a 30-minute dry Finish sauna treatment., The same exercise training program without the sauna treatments
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Joanna KarolkiewiczDepartment of Food and Nutrition, Poznan University of Physical Education, Poznań, Poland. karolkiewicz@awf.poznan.pl.
David C NiemanDepartment of Biology, Appalachian State University, North Carolina Research Campus, Kannapolis, NC, USA.
Tomasz CisońDepartment of Physiotherapy, Institute of Physical Education, State University of Applied Sciences in Nowy Sącz, Nowy Sącz, Poland.
Joanna SzurkowskaDepartment of Food and Nutrition, Poznan University of Physical Education, Poznań, Poland.
Mirosława GałęckaInstitute of Microecology, Poznań, Poland.
Dariusz SitkowskiDepartment of Physiology, Institute of Sport - National Research Institute PL, Warsaw, Poland.
Zbigniew SzygulaDepartment of Sports Medicine and Human Nutrition, University of Physical Education, Kraków, Poland.
Appalachian State University · USInstytut Sportu · PLPaństwowa Wyższa Szkoła Zawodowa w Nowym Sączu · PLUniversity School of Physical Education in Kraków · PL

Funding

State University of Applied Sciences in Nowy Sącz PB.501-1/2018
6 · The paper itself

Abstract

backgroundBody temperature fluctuations induced by acute exercise bouts may influence the intestinal barrier with related effects on epithelial permeability, immune responses, and release of metabolites produced by the gut microbiota. This study evaluated the effects of post-exercise sauna bathing in young men undergoing endurance training on gut bacteria inflammation and intestinal barrier function.

methodsFifteen (15) untrained males aged 22 ± 1.5 years were randomly assigned to exercise training (ET) with or without post-exercise sauna treatments (S). Participants in the group ET + S (n = 8) exercised 60 min, 3 times per week, on a bicycle ergometer followed by a 30-min dry Finish sauna treatment. The control group (ET, n = 7) engaged in the same exercise training program without the sauna treatments. Blood and stool samples were collected before and after the 4-week training program. Blood samples were analysed for the concentration of high-sensitivity C-reactive protein (hsCRP) and complete blood counts. Stool samples were analysed for pH, quantitative and qualitative measures of targeted bacteria, zonulin, and secretory immunoglobulin A.

resultsInteraction effects revealed no differences in the pattern of change over time between groups for the abundance of selected gut microbiome bacteria and stool pH, zonulin, sIgA, and hsCRP. Pre- and post-study fecal concentrations of Bifidobacterium spp., Faecalibacterium prausnitzii, and Akkermansia muciniphila were below reference values for these bacteria in both groups.

conclusionsThe combination of 4-weeks exercise followed by passive heat exposure did not have a measurable influence on targeted gut microbiota, intestinal barrier function, and hsCRP levels in young males.

trial registrationThe study was retrospectively registered in the clinical trials registry (Clinicaltrials.gov) under the trial registration number: NCT05277597. Release Date: March 11, 2022.

Indexed as

ExerciseGut microbiotaIntestinal barrier functionSauna bathing

Identifiers

PMID35710395
PMCPMC9202095
OpenAlexW4283030923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.