Evidence map›Paper›PMID 35710252›Full record

ArticleBMJ open2022

Coprescribing of opioids and high-risk medications in the USA: a cross-sectional study with data from national ambulatory and emergency department settings.

Kara Suvada, Anna Zimmer, Jesse Soodalter, Jimi S Malik, Dio Kavalieratos, Mohammed K Ali

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kara SuvadaDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA ksuvada@emory.edu.ORCID 0000-0003-2785-835X
Anna ZimmerSchool of Medicine, Emory University, Atlanta, Georgia, USA.
Jesse SoodalterDivision of Palliative Medicine, Department of Family and Preventive Medicine, School of Medicine, Emory University, Atlanta, Georgia, USA.
Jimi S MalikDivision of Palliative Medicine, Department of Family and Preventive Medicine, School of Medicine, Emory University, Atlanta, Georgia, USA.
Dio KavalieratosDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Mohammed K AliDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Emory University · US

Funding

INTEGRATING PALLIATIVE CARE WITH DISEASE MANAGEMENT TO IMPROVE OUTCOMES AMONG PATIENTS WITH ADVANCED HEART FAILURE: INTERVENTIONAL RESEARCH CAREER DEVELOPMENTK01HL133466 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KAVALIERATOS, DIONYSIOS · 2016 to 2019
$527k
NHLBI NIH HHS K01 HL133466
6 · The paper itself

Abstract

objectiveDescribe trends in opioid plus high-risk medication coprescribing in the USA.

designAnalyses of serial, cross-sectional, nationally representative data of the National Ambulatory Medical Care Survey (NAMCS) over 2007-2016 and the National Hospital Ambulatory Medical Care Survey (NHAMCS) over 2007-2018.

settingUS ambulatory (NAMCS) and emergency department (ED, NHAMCS) settings.

participantsPatient visits in which the patient was 18 years and older with an opioid prescription in the NAMCS or NHAMCS databases. PRIMARY AND SECONDARY OUTCOME MEASURES: Frequency of opioid plus high-risk medication coprescribing.

resultsFrom a combined sample of 700 499 visits over 2007-2018, there were 105 720 visits (15.1%) where opioids were prescribed. n=31 825 were from NAMCS and n=73 895 were from NHAMCS. The mean prevalence of coprescription of opioids and high-risk medications for the combined NAMCS and NHAMCS sample was 18.4% in 2007, peaked at 33.2% in 2014 and declined to 23.8% in 2016. Compared with adults receiving opioid prescriptions alone, those coprescribed opioids and high-risk medications were older, more likely female, white and using private or Medicare insurance (p<0.0001).

conclusionsCoprescribing is more common in ambulatory than ED settings and has been declining, yet one in four patient visits where opioids were prescribed resulted in coprescribed, high-risk medications in 2016. Efforts and research to help lower the rates of high-risk prescribing are needed.

Indexed as

Analgesics, OpioidMedicareAdultAgedAmbulatory CareCross-Sectional StudiesEmergency Service, HospitalFemaleHealth Care SurveysHumansPractice Patterns, Physicians'United StatesAnalgesics, Opioidepidemiologypain managementprimary carerisk management

Identifiers

PMID35710252
PMCPMC9207755
OpenAlexW4282970980

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.