Evidence map›Paper›PMID 35710033›Full record

ArticleDevelopmental biology2022

Molecular characterization of a flatworm Girardia isolate from Guanajuato, Mexico.

Elizabeth M Duncan, Stephanie H Nowotarski, Carlos Guerrero-Hernández, Eric J Ross, Julia A D'Orazio, Clubes de Ciencia México Workshop for Developmental Biology, Sean McKinney, Mark C McHargue, Longhua Guo, Melainia McClain and 1 more

Open access · greenAbstract read
In one paragraph

Article in Developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Elizabeth M DuncanUniversity of Kentucky, Lexington, KY, USA.
Stephanie H NowotarskiStowers Institute for Medical Research, Kansas City, MO, USA; Howard Hughes Medical Institute, Kansas City, MO, USA.
Carlos Guerrero-HernándezStowers Institute for Medical Research, Kansas City, MO, USA.
Eric J RossStowers Institute for Medical Research, Kansas City, MO, USA; Howard Hughes Medical Institute, Kansas City, MO, USA.
Julia A D'OrazioUniversity of Kentucky, Lexington, KY, USA.
Clubes de Ciencia México Workshop for Developmental Biology
Sean McKinneyStowers Institute for Medical Research, Kansas City, MO, USA.
Mark C McHargueUniversity of Kentucky, Lexington, KY, USA.
Longhua GuoUniversity of California, Los Angeles, CA, USA.
Melainia McClainStowers Institute for Medical Research, Kansas City, MO, USA.
Alejandro Sánchez AlvaradoStowers Institute for Medical Research, Kansas City, MO, USA; Howard Hughes Medical Institute, Kansas City, MO, USA. Electronic address: asa@stowers.org.
Stowers Institute for Medical Research · USUniversity of Kentucky · USUniversity of California, Los Angeles · US

Funding

University of Kentucky Center for Cancer MetabolismP20GM121327 · NIGMS · UNIVERSITY OF KENTUCKY · PI Jianhang Jia · 2017 to 2026
$25.0M
The molecular basis of planarian regenerationR37GM057260 · NIGMS · UNIVERSITY OF UTAH · PI SANCHEZ ALVARADO, ALEJANDRO · 2009 to 2018
$2.8M
The role of muscle contraction in gene activation and tissue regenerationR35GM142679 · NIGMS · UNIVERSITY OF KENTUCKY · PI DUNCAN, ELIZABETH MARIE · 2021 to 2025
$2.0M
Howard Hughes Medical InstituteNIGMS NIH HHS P20 GM121327NIGMS NIH HHS R35 GM142679NIGMS NIH HHS R37 GM057260
6 · The paper itself

Abstract

Planarian flatworms are best known for their impressive regenerative capacity, yet this trait varies across species. In addition, planarians have other features that share morphology and function with the tissues of many other animals, including an outer mucociliary epithelium that drives planarian locomotion and is very similar to the epithelial linings of the human lung and oviduct. Planarians occupy a broad range of ecological habitats and are known to be sensitive to changes in their environment. Yet, despite their potential to provide valuable insight to many different fields, very few planarian species have been developed as laboratory models for mechanism-based research. Here we describe a previously undocumented planarian isolate, Girardia sp. (Guanajuato). After collecting this isolate from a freshwater habitat in central Mexico, we characterized it at the morphological, cellular, and molecular level. We show that Girardia sp. (Guanajuato) not only shares features with animals in the Girardia genus but also possesses traits that appear unique to this isolate. By thoroughly characterizing this new planarian isolate, our work facilitates future comparisons to other flatworms and further molecular dissection of the unique and physiologically-relevant traits observed in this Girardia sp. (Guanajuato) isolate.

Indexed as

PlanariansAnimalsEcosystemHumansMexicoGirardiaMexicoPlanarianRegenerationStem cells

Identifiers

PMID35710033
PMCPMC11104013
OpenAlexW4282839995

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.