Evidence map›Paper›PMID 35709828›Full record

ArticleNature2022

Spatial profiling of early primate gastrulation in utero.

Sophie Bergmann, Christopher A Penfold, Erin Slatery, Dylan Siriwardena, Charis Drummer, Stephen Clark, Stanley E Strawbridge, Keiko Kishimoto, Alice Vickers, Mukul Tewary and 6 more

Open access · greenAbstract read
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 149 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Census and genetic analysis of the United States marmoset population.bioRxiv : the preprint server for biology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Mechanisms of human germ cell development.Nature reviews. Molecular cell biology · 2026
    Review
  13. Remodeling ofScience advances · 2026
    Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 3 countries.

Sophie Bergmann *Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
Christopher A Penfold *Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0001-5823-4705
Erin Slatery *Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-9097-6618
Dylan SiriwardenaDepartment of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
Charis DrummerResearch Platform Degenerative Diseases, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany.
Stephen ClarkCentre for Trophoblast Research, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-6183-491X
Stanley E StrawbridgeDepartment of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-0273-0835
Keiko KishimotoDepartment of Marmoset Biology and Medicine, Central Institute for Experimental Animals, Kawasaki, Japan.
Alice VickersCentre for Stem Cells and Regenerative Medicine, King's College London, Guy's Hospital, London, UK.ORCID http://orcid.org/0000-0001-9149-4744
Mukul TewaryCentre for Stem Cells and Regenerative Medicine, King's College London, Guy's Hospital, London, UK.
Timo N KohlerDepartment of Biochemistry, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-1949-0655
Florian HollfelderDepartment of Biochemistry, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-1367-6312
Wolf ReikCentre for Trophoblast Research, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0003-0216-9881
Erika SasakiDepartment of Marmoset Biology and Medicine, Central Institute for Experimental Animals, Kawasaki, Japan.ORCID http://orcid.org/0000-0002-0415-5400
Rüdiger BehrResearch Platform Degenerative Diseases, German Primate Center, Leibniz Institute for Primate Research, Göttingen, Germany.ORCID http://orcid.org/0000-0001-8816-6619
Thorsten E BoroviakDepartment of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK. teb45@cam.ac.uk.ORCID http://orcid.org/0000-0001-8703-8949
Wellcome/MRC Cambridge Stem Cell Institute · GBBabraham Institute · GBCentral Institute for Experimental Animals · JPGerman Primate Center · DEGuy's Hospital · GBUniversity of Cambridge · GB

Funding

Wellcome Trust 206684Wellcome Trust 206684/Z/17/ZWellcome Trust WT108438/C/15/ZWellcome Trust WT RG89228
6 · The paper itself

Abstract

Gastrulation controls the emergence of cellular diversity and axis patterning in the early embryo. In mammals, this transformation is orchestrated by dynamic signalling centres at the interface of embryonic and extraembryonic tissues

Indexed as

CallithrixGastrulationUterusAnimalsCell DifferentiationEmbryo, MammalianEndodermFemaleGene Expression ProfilingGerm LayersHumansPluripotent Stem Cells

Identifiers

PMID35709828
PMCPMC7614364
OpenAlexW4283015409

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.