Evidence map›Paper›PMID 35709826›Full record

ArticleThe Lancet. Respiratory medicine2022

Early-phase clinical trials in a pandemic: learning from the response to COVID-19.

Alex Horsley, Chris Brightling, Jane Davies, Ratko Djukanovic, Liam G Heaney, Tracy Hussell, Stefan J Marciniak, Lorcan McGarvey, Joanna C Porter, Thomas Wilkinson and 2 more

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The Lancet. Respiratory medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Alex HorsleyDivision of Infection, Immunity and Respiratory Medicine, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
Chris BrightlingLeicester NIHR Biomedical Research Centre and Department of Respiratory Sciences, University of Leicester, Leicester, UK.
Jane DaviesRoyal Brompton and Harefield NHS Foundation Trust and Imperial College London, London UK.
Ratko DjukanovicNIHR Southampton Biomedical Research Centre and School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
Liam G HeaneyWellcome Wolfson Institute for Experimental Medicine, Queens University, Belfast, UK.
Tracy HussellDivision of Infection, Immunity and Respiratory Medicine, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
Stefan J MarciniakCambridge University Hospitals NHS Foundation Trust, Royal Papworth Hospital NHS Foundation Trust, and University of Cambridge, Cambridge, UK.
Lorcan McGarveyWellcome Wolfson Institute for Experimental Medicine, Queens University, Belfast, UK.
Joanna C PorterUCL Department of Respiratory Medicine, UCL, and UCLH NHS Foundation Trust, London, UK.
Thomas WilkinsonNIHR Southampton Biomedical Research Centre and School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
Ling-Pei HoOxford NIHR Biomedical Research Centre and MRC Human Immunology Unit, University of Oxford, Oxford, UK. Electronic address: ling-pei.ho@imm.ox.ac.uk.
NIHR Respiratory Translational Research Collaboration network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19PandemicsHumansSARS-CoV-2

Identifiers

PMID35709826
PMCPMC9191862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.