Evidence map›Paper›PMID 35709421›Full record

ArticleJCO oncology practice2022

Financial Toxicity Intervention Improves Outcomes in Patients With Hematologic Malignancy.

Thomas G Knight, Melissa Aguiar, Myra Robinson, Allison Morse, Tommy Chen, Rupali Bose, Jing Ai, Brittany K Ragon, Aleksander L Chojecki, Nilay A Shah and 4 more

Abstract read
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In one paragraph

Article in JCO oncology practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
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  8. Review
  9. Health disparities in neurology.Nature reviews. Neurology · 2025
    Review
  10. Article
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  12. Associations between financial toxicity, health-related quality of life, and well-being in Indonesian patients with breast cancer.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
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  20. Cancer survivor preferences on the timing and content of interventions to mitigate financial toxicity associated with cancer treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Thomas G KnightDepartment of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC.ORCID 0000-0002-9864-7413
Melissa AguiarLevine Cancer Institute, Atrium Health, Charlotte, NC.ORCID 0000-0002-9993-8925
Myra RobinsonDepartment of Cancer Biostatistics, Levine Cancer Institute, Atrium Health, Charlotte, NC.ORCID 0000-0002-6933-889X
Allison MorseLevine Cancer Institute, Atrium Health, Charlotte, NC.
Tommy ChenDepartment of Cancer Biostatistics, Levine Cancer Institute, Atrium Health, Charlotte, NC.
Rupali BoseDepartment of Cancer Biostatistics, Levine Cancer Institute, Atrium Health, Charlotte, NC.
Jing AiDepartment of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC.
Brittany K RagonDepartment of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC.ORCID 0000-0002-2460-0698
Aleksander L ChojeckiDepartment of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC.ORCID 0000-0003-2841-8321
Nilay A ShahDepartment of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC.
Srinivasa R SanikommuDepartment of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC.
James SymanowskiDepartment of Cancer Biostatistics, Levine Cancer Institute, Atrium Health, Charlotte, NC.ORCID 0000-0003-2495-8822
Edward A CopelanDepartment of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC.
Michael R GrunwaldDepartment of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC.
Levine Cancer Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePatients with hematologic malignancies are extremely vulnerable to financial toxicity (FT) because of the high costs of treatment and health care utilization. This pilot study identified patients at high risk because of FT and attempted to improve clinical outcomes with comprehensive intervention.

methodsAll patients who presented to the Levine Cancer Institute's Leukemia Clinic between May 26, 2019, and March 10, 2020, were screened for inclusion by standardized two question previsit survey. Patients screening positive were enrolled in the comprehensive intervention that used nurse navigators, clinical pharmacists, and community pro bono financial planners. Primary outcomes were defined as improvement in mental and physical quality of life in all patients and improvement in overall survival in the high-risk disease group.

resultsOne hundred seven patients completed comprehensive intervention. Patients experiencing FT had increased rates of noncompliance including to prescription (16.8%) and over-the-counter medications (15.9%). The intervention resulted in statistically significantly higher quality of life when measured by using Patient-Reported Outcomes Measurement Information System physical (12.5 ± 2.2

conclusionScreening and intervention on FT for patients with hematologic malignancies is associated with increased quality of life and survival.

Indexed as

Hematologic NeoplasmsQuality of LifeFinancial StressHumansPilot ProjectsSurveys and Questionnaires

Identifiers

PMID35709421
OpenAlexW4283020070

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.