Evidence map›Paper›PMID 35709253›Full record

ArticlePLoS neglected tropical diseases2022

Effect of clinician information sessions on diagnostic testing for Chagas disease.

Helen Mahoney West, Carly E Milliren, Jennifer Manne-Goehler, Jillian Davis, Jaime Gallegos, Juan Huanuco Perez, Julia R Köhler

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. An Evidence-Based Intervention to IncreaseOpen forum infectious diseases · 2025
    Article
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  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Helen Mahoney WestDivision of Infectious Disease Boston Children's Hospital, Boston, Massachusetts, United States of America.ORCID 0000-0003-0282-9069
Carly E MillirenInstitutional Centers for Clinical and Translational Research, Boston Children's Hospital, Boston, Massachusetts, United States of America.
Jennifer Manne-GoehlerMassachusetts General Brigham Hospital, Boston, Massachusetts, United States of America.ORCID 0000-0001-9295-0035
Jillian DavisEast Boston Neighborhood Health Center, Boston, Massachusetts, United States of America.ORCID 0000-0003-4036-2578
Jaime GallegosEast Boston Neighborhood Health Center, Boston, Massachusetts, United States of America.
Juan Huanuco PerezEast Boston Neighborhood Health Center, Boston, Massachusetts, United States of America.
Julia R KöhlerDivision of Infectious Disease Boston Children's Hospital, Boston, Massachusetts, United States of America.
Boston Children's Hospital · USNeighborhood Health · USMassachusetts General Hospital · US

Funding

Bridging Neglect: improved access to high-quality heart health information and care for communities at risk of Chagas diseaseG08LM013191 · NLM · BOSTON CHILDREN'S HOSPITAL · PI KOEHLER, JULIA R, LEVIN, LEONARD L · 2019 to 2021
$436k
NLM NIH HHS G08 LM013191
6 · The paper itself

Abstract

backgroundChagas disease is a potentially life-threatening neglected disease of poverty that is endemic in continental Latin America. Caused by Trypanosoma cruzi (T. cruzi), it is one of six parasitic diseases in the United States targeted by the Centers for Disease Control as a public health problem in need of action. An estimated 300,000 people are infected with T. cruzi in the United States (US). Although its morbidity, mortality and economic burden are high, awareness of Chagas disease is lacking among many healthcare providers in the US. The purpose of this analysis is to determine if the number of diagnostic tests performed at a community health center serving an at-risk population for Chagas disease increased after information sessions. A secondary aim was to determine if there was a difference by provider type, i.e., nurse practitioner vs. physician, or by specialty in the number of patients screened. METHODOLOGY/PRINCIPAL

findingsWe conducted a retrospective data analysis of the number of Chagas serology tests performed at a community health center before and after information sessions for clinicians. A time series analysis was conducted focusing on the Adult and Family Medicine Departments at East Boston Neighborhood Health Center (EBNHC). Across all departments there were 1,957 T. cruzi tests performed before the sessions vs. 2,623 after the sessions. Interrupted time series analysis across departments indicated that testing volume was stable over time prior to the sessions (pre-period slope = +4.1 per month; p = 0.12), followed by an immediate shift after the session (+51.6; p = 0.03), while testing volume remained stable over time after the session (post-period slope = -6.0 per month; p = 0.11). CONCLUSION/SIGNIFICANCE: In this study, Chagas testing increased after information sessions. Clinicians who began testing their patients for Chagas disease after learning of the importance of this intervention added an extra, potentially time-consuming task to their already busy workdays without external incentives or recognition.

Indexed as

Chagas DiseaseTrypanosoma cruziAdultHumansNeglected DiseasesRetrospective StudiesSerologic TestsUnited States

Identifiers

PMID35709253
PMCPMC9242495
OpenAlexW4282972238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.